clinical tool Articles
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An independent assessment of AI for prostate cancer detection - Case Study
Yale Medicine, an academic medical center with a high volume of prostate biopsies, conducted a study to determine Paige Prostate’s utility as a prescreening tool for clinical use. A total of 1,876 prostate core biopsy slides were analyzed by Paige Prostate, and only those cores categorized by the AI as “suspicious” or as out of distribution were manually reviewed by Yale ...
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Diamond coated microtools for machining compact bone
The structure of compact bone is heterogeneous and as such, is difficult to shape by cutting tools during clinical surgical practices. The structure of bone can have a devastating effect on the performance of the cutting tool unless it is coated with a thin solid film that is wear resistant. The paper investigates the use of diamond coated cutting tools to prepare bone for prosthetic implants and ...
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Are clinicians delivering the best care for patients with bladder and bowel dysfunction? A recent study suggests otherwise
People with neurogenic bladder and/or bowel dysfunction often suffer from highly individualized symptoms. It can be difficult to quantify change in an individual’s symptoms using standardized measurement tools, and points to the value of Patient—Centered Outcome Measures. As a relatively new concept, Patient—Centered Outcome Measures (PCOM) aims to place patients, their ...
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7 Medical Calculators for Celiac Disease Diagnosis - Case Study
This case study is presented to highlight how medical calculators can be useful clinical decision making tools for celiac disease diagnosis. Throughout the discussion, links to medical calculators that healthcare providers can use are provided. Incorporating these resources into a clinician’s workflow can lead to better outcomes through more accurate diagnoses and better management for this ...
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Advancing patient care for Japan`s most common cancer - Case Study
Challenge Calculating the appropriate sample size for a first of its kind stage-II colon cancer trial As Chairman of the Department of Biostatistics, Professor Satoshi Teramukai leads a variety of investigator-initiated clinical trials at the Kyoto Prefectural University of Medicine. With over 35 years experience, hundreds of published papers and thousands of citations, Professor Satoshi ...
By Statsol
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What is Sepsis? Key Symptoms, Potential Complications, and Vital Treatment
The term sepsis describes the body's extreme response to infection. When a person suffers from sepsis, his or her immune system has been triggered in response to an infection, which causes inflammation and damages tissues in the body. Symptoms of Sepsis The symptoms of sepsis may include: Fever (102 degrees Fahrenheit or higher) Chills Rapid breathing (above 20 breaths per minute) or ...
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Newly Released FDA Guidelines for Sepsis Detection & what it Means for Hospitals
Executive Brief On September 28, 2022, the FDA released Clinical Decision Support, Guidance for Industry and Food and Drug Administration Staff. This guidance is long overdue, and with it comes the elimination of any protections for EHRs, or any other vendors, to pretend it’s OK to sell or deploy solutions for patient monitoring and care for life-threatening conditions like sepsis, that ...
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Essential Clinical Trial Systems for Small, Midsize, and Large Pharma
Revisiting the “why” behind decision making can be a helpful exercise in all aspects of business. This is no less true for clinical operations executives when it comes to the clinical trial systems they employ to facilitate their teams’ work. The technology that supports clinical trial systems has evolved steadily over the past several decades, yet the ultimate goal of ...
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Focus On These 4 Things to Accelerate Clin Ops Productivity
Whether your clinical operations team sits in a large sponsor company, or in one that’s still growing, it must be supported by efficient systems to maintain high productivity. Clinical trial protocols must be conducted with quality, within budget, and within timelines. To achieve this, Clinical Program Managers and their teams must be able to rely on 4 things: A strong ...
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Barriers to data sharing in today’s healthcare landscape
In today’s healthcare environment, the general consensus is that the exchange and flow of data is crucial and beneficial to developing better care of the patients. Healthcare information exchanges (HIEs), as an example, have shown to be effective in improving public health, reducing healthcare redundancies, and providing clinical providers with more support tools in their day-to-day work. ...
By Segmed, Inc.
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ELISpot for measuring human immune responses to vaccines
The enzyme-linked immunosorbent spot (ELISpot) assay is one of the most commonly used methods to measure antigen-specific T cells in both mice and humans. Some of the primary reasons for the popularity of the method are that ELISpot is highly quantitative, can measure a broad range of magnitudes of response and is capable of assessing critical cellular immune-related activities such as IFN-g ...
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Results support feasibility of entirely extracardiac, minimally invasive, temporary pacing system
New results support the feasibility of an entirely extracardiac pacing method in a heterogeneous patient population, using a minimally invasive, parasternal delivery approach, with adequate sensing and thresholds suited for temporary pacing. The study, authored by Anne-Floor BE Quast, Niek EG Beurskens (University of Amsterdam, The Netherlands) and colleagues, was recently published in ...
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Applications of Metagenomics in Biotechnology and Health Care
Microbes are present almost everywhere. They play a vital role in cycling carbon, release important compounds, and may be associated with infectious diseases. Metagenomics is the culture-independent genomic research of microbial communities. Metagenomics presents a powerful tool to study prokaryotes and viruses in the environment via the analysis of their DNA obtained directly from environmental ...
By CD Genomics
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Applications of Metagenomics in Biotechnology and Health Care
Microbes are present almost everywhere. They play a vital role in cycling carbon, release important compounds, and may be associated with infectious diseases. Metagenomics is the culture-independent genomic research of microbial communities. Metagenomics presents a powerful tool to study prokaryotes and viruses in the environment via the analysis of their DNA obtained directly from environmental ...
By CD Genomics
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Introducing Navigating Cancer’s Medical Advisory Board Ahead of ASCO Presentations Illustrating Equitable Cancer Care Innovation
Navigating Cancer is filling an important role in the healthcare community during a time that has placed tremendous pressure on healthcare providers to better support a growing and diverse patient population, outside-of-the-clinic. Digital health tools and remote symptom monitoring enable more efficient care delivery and improve patient outcomes – while providing actionable insights based ...
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Improved Sepsis Detection & Compliance: 6 Areas your Next Solution should Address
Sepsis accounts for over 20% of deaths worldwide (WHO) and 85% of cases occur in low-resource settings.But this isn’t a problem mostly owned by third-world countries with inadequate equipment and detection technology. In the U.S., less than 50% of patients are correctly treated for sepsis, mostly due to clinicians missing the timeline for treatment. The problem is so widespread that ...
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Driving Data-driven Medicine to Advance Personalized Care
Clinical trials are often designed with the participant’s everyday life in mind – trying to gather as much clinically-relevant data in a controlled manner as possible while allowing individuals to live their regular lives. However, it is true that trials are artificial environments, and participants are actively monitored to ensure their safety and to determine the efficacy of a drug ...
By AiCure
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Benefits of point of care PFT in Rural Health
There’s an island in northern Lake Michigan called Beaver Island. It sits roughly 30 miles offshore of Michigan’s Lower Peninsula, part of an archipelago of other whimsically named islands (including Whiskey, Hog, Garden, and Hat). Roughly 500 hardy souls call Beaver Island home year-round, and the two townships that occupy the land support a small but stable economy that embodies the ...
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5 Key Considerations for Patient Monitoring during a Pandemic
The use of patient monitoring has surged during COVID-19. Here’s what health providers should know about patient monitoring during a pandemic, and beyond. The COVID-19 pandemic has shifted the way care is delivered on a fundamental level. What was once an up-and-coming tool for improved care delivery — namely, advanced patient monitoring technology — is now at the forefront of ...
By EarlySense
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