Clinical Toxicology Articles & Analysis
4 articles found
Understanding the function and importance of cytochrome P450 is essential for fields ranging from pharmacology to toxicology and clinical medicine. Structure and Function Cytochrome P450 enzymes are named for their ability to absorb light at a wavelength of 450 nm when bound to carbon monoxide. ...
Appropriate methods should be used to conduct comparability studies on toxicological batches, clinical batches, and commercial batches.Payload-Linker IntermediateRegulatory requirements for payload-linker intermediates and final DS are the same. ...
The opioid crisis in the United States is a devastating public health issue, with over 70,000 overdose deaths annually, largely driven by the highly potent synthetic opioid fentanyl. The urgency to address this crisis has spurred the development of innovative therapies to prevent and reverse fentanyl overdoses. In this blog, we will explore the groundbreaking preclinical work on CSX-1004, a fully ...
His talk, and those of others at the recent Symposium on Mass Spectrometry for the Modern Clinical Laboratory, made one point perfectly clear: in their laboratories, liquid chromatography-mass spectrometry is dramatically changing clinical practice. ...