Cystic Fibrosis Articles & Analysis: Older
15 articles found
Gene delivery can be used to treat a wide range of diseases, including inheritable diseases similar to cystic fibrosis and sickle cell anemia. By introducing a functional gene into the cells with these symptoms, researchers hope to correct the inherited gene mutation and potentially cure the disease. ...
This process is exacerbated by factors such as smoking, which triggers an inflammatory response that increases elastase release. In cystic fibrosis, another respiratory condition, mutations in a specific gene lead to the production of thick mucus in the lungs. ...
What is biofilm? Biofilms are defined as communities of micro-organisms attached to a surface, or one another, and encased within a matrix of extracellular polymeric substance (EPS). The EPS makes up the largest component of the biofilm, and in the biological environment is generally composed of polysaccharides, proteins, glycolipids, blood products, cellular debris, extracellular enzymes, metal ...
For instance, mouse models have been influential in studying conditions like cystic fibrosis, Huntington's disease, and inherited metabolic disorders. ...
Applications in the Pharmaceutical Industry Digestive Disorders: Native Porcine Pancreatin is crucial in the treatment of digestive disorders, such as cystic fibrosis and chronic pancreatitis. Individuals with these conditions often suffer from insufficient endogenous enzyme production. ...
What is cystic fibrosis? Cystic fibrosis (CF) is a rare genetic disorder that affects the lungs, digestive system, and other organs. ...
Aberrant protein degradation, in fact, is also a pathogenic mechanism in some diseases, such as cystic fibrosis (CF) and some forms of cancer. Therefore, for these diseases, targeted protein stabilizers (TPS), rather than targeted protein degraders (TPD), need to be developed. ...
Many cell and gene therapy solutions have shown considerable promise as a source of possible treatments for a wide range of chronic disorders. However, these sophisticated therapies introduce additional barriers such as the requirements for ultra-low and cryogenic storage, which affect numerous steps of the biomedical solutions’ life cycles, from their development to their administration. ...
For example, diversity for a sickle cell population is different than that of cystic fibrosis, and the diversity needed for an AI-powered population screening tool is different from one used to track a patient’s symptoms. ...
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The makeup and needs of a trial for sickle cell anemia are drastically different than those for cystic fibrosis – and the algorithms need to be trained accordingly. ...
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We maintain our commitment to their diagnosis, with kits for the in vitro diagnosis of the following rare diseases*: Rare Disease : Diagnostic tests Cystic fibrosis or fibrocystic disease of the pancreas : Determination of 50 cystic fibrosis mutations in patients and relatives by genetic analysis Multiple sclerosis : ...
Spirometry can also be helpful to start trimming down a list of differential diagnoses, being able to indicate potential problems in the upper airway (such as vocal cord dysfunction) and highlight restrictive patterns that can indicate disease conditions like pulmonary fibrosis. More importantly, modern units like the EasyOne® Air can be easily integrated into workflows in ...
Inflammatory Gut Diseases are Complex Inflammation is a key factor in many intestinal diseases, including cancer, celiac disease, cystic fibrosis, irritable bowel disease (IBS), and inflammatory bowel disease (IBD). ...
A simple illustration of this is issue is conventional modeling of cystic fibrosis (CF) in 3D gut tissue culture. Generally, the GI form of the disease is caused by a single or compound mutations that cause improper mucous hydration and clinical sequela in the small intestine. ...
VOC biomarkers have been used to diagnose and/or manage multiple respiratory diseases such as asthma, COPD, cystic fibrosis, tuberculosis, and ventilator-assisted pneumonia. Unfortunately, the gold standard method of detection, gas chromatography/mass spectrometry (GC/MS), is a large, lab-based technology requiring highly trained technical staff to process ...