Cystic Fibrosis Articles & Analysis: This-Year
1 articles found
Key pathologies associated with excessive ELANE activity include: l Chronic obstructive pulmonary disease (COPD): ELANE-mediated degradation of lung elastin contributes to alveolar destruction and emphysema. l Cystic fibrosis (CF): Neutrophilic inflammation in the CF lung is exacerbated by high ELANE levels, promoting mucus hypersecretion, airway remodeling, ...