diabetes and obesity Articles
-
Project - Sublingual Dual Incretin Inhibitor (GLP-1/GIP)
Biolingus explores the development of a sublingual dual incretin inhibitor. BioLingus will position these products in the “epidemic” markets of obesity and type II diabetes : More than 400 MM people suffer from diabetes today. The global type 2 diabetes market is expected to grow to $58.7 billion by 2025, with an annual growth rate of 6.5%, according to research and consulting ...
By BioLingus AG
-
Three ways you can help your health while helping the environment
When you look to the year ahead, what do you see? Ensia recently invited eight global thought leaders to share their thoughts. In this interview Jonathan Patz, director of the Global Health Institute at the University of Wisconsin-Madison, responds to three questions: What will be the biggest challenge to address or opportunity to grasp in your field in 2017? Why? And what should we be doing ...
By Ensia
-
Suppressive effect of low-dose X-irradiation on type I diabetes non-obese diabetic (NOD) mice
We examined the effect of X-irradiation (0, 0.25, 0.5 or 1.0 Gy) on the onset of the type I diabetes (insulin dependent diabetes mellitus) in non-obese diabetic (NOD) mice. NOD mice are characterised by a progressive loss of insulin-producing β-cells in the pancreas by autoimmune mechanisms. The destruction of β-cells is known to be due to apoptosis induced by oxidative stress caused by ROS. In ...
-
The role of anthropometric indices in predicting comorbidities of obesity in a rural Egyptian population
Obesity is associated with higher prevalence of type2 diabetes and hypertension. Objectives were determining prevalence of obesity, type2 diabetes and hypertension in a rural village. This cross sectional study included 1,000 male and female ≥ 20 years. Blood pressure, anthropometry, fasting and 2 hr post-prandial glucose were determined. Results showed 29.7% overweight and 45.6% obese. Visceral ...
-
The Health Effects of Probiotics on the Human Body
Probiotics are a type of active microorganisms that play a role by improving the balance of the host's intestinal microflora. They can produce definite health effects to improve the host's microecological balance and play a beneficial role. In 2001, the World Food and Agriculture Organization (FAO) and the World Health Organization (WHO) also defined probiotics as follows: Live bacteria that can ...
-
The Effect of Probiotics for the Gut Health
There are trillions of microbes inhabiting the human intestine. These microbes gradually reach a balance of types and numbers during the process of reproduction, and this balance is closely related to the body's normal metabolism. Once the structure of the intestinal flora becomes imbalanced, various metabolic diseases will follow. The probiotics multiply in large quantities in the intestine, ...
-
Involvement of the inorganic phosphate transporter Pit1 in insulin signaling and metabolism - Case Study
PiT1, initially identified as retrovirus receptor, is a transmembrane protein of the sodium-phosphate co-transporter family. PiT1 also has independent functions of its role as a phosphate transporter, notably on cell proliferation, adhesion or apoptosis. These observations suggest that interactions of PiT1 with other molecular partners may impact not only the homeostasis of inorganic phosphate, ...
By Inovarion
-
Overview of Diabetes: Prevalence Assessment, Treatment And Prevention
Diabetes is a chronic disease that affects more than 540 million people worldwide and is one of the leading causes of death and disability worldwide. In China, there are more than 114 million adults with diabetes, accounting for about a quarter of the world's diabetes patients. With the change of living and eating habits, diabetes has become the third major factor affecting human health after ...
-
Breakdown of How Sugar Impacts The Brain and Cognitive Function
It is no secret that glucose, a form of sugar, is the main source of energy for every cell in our bodies, including our brain cells. Because the brain is packed with neurons, it uses more energy than any other organ in the body. Our brains reward us for consuming sugar. Whether you are eating a delicious meal, sharing a kiss with someone you love, or enjoying a sugary treat, the mesolimbic ...
-
Arteriovenous Fistulae for Haemodialysis: A Systematic Review and Metaanalysis of Efficacy and Safety Outcomes
Background: Arteriovenous fistulae are the currently recommended gold standard vascular access modality for haemodialysis because of their prolonged patency, improved durability, and low risk of infection for those that mature. However, notable disadvantages are observed in terms of protracted maturation time, associated high rates of catheter use, and substantial abandonment rates. The aim of ...
-
What causes heart failure with preserved ejection fraction (HFpEF)?
Heart failure with preserved ejection fraction (HFpEF) is a multifactorial and multisystemic disorder that represents more than 50% of all heart failure cases.[1] Epidemiologic data from the Framingham Study, an international cohort study, shows a rapid increase in the prevalence of HFpEF over the past three decades, from 41% to 56% and, conversely, a decrease in the prevalence of HFrEF from 44% ...
-
Standing Desk Is Value For Money
The study found that giving 20% staff a standing desk in the office would save A$84 million in health care costs. According to Australia's first assessment of a low cost standing desk, providing a standing office desk for 20% of office staff can save $8,400 in health care costs and prevent obesity, type 2 diabetes and cardiovascular disease and increase the total life of 7492. The researchers ...
-
A Closer Look at Metabolic Disease Models and Diabetes Models
Diabetes, specifically Type 1 and Type 2 Diabetes Mellitus, remains one of the most commonly encountered metabolic diseases worldwide. The complexity and diversity of these conditions necessitate the development of detailed medical models for a comprehensive understanding of the diseases. Over time, Type 1 and Type 2 Diabetes Mellitus Models, Metabolic Disease Models, and generalized Diabetes ...
-
How good air quality and a healthy routine can help you sleep better
The importance of a good night’s rest can’t be overstated. There is a reason why depriving someone of sleep is a form of torture. Humans need regular periods of quality sleep to recharge, process the day’s experiences, file away memories and follow a normal circadian rhythm to regulate the body’s functions. The amount of sleep we need varies with each person and is ...
-
Nonalcoholic Fatty Liver and How Fucoxanthin Might Help
Many may not have heard of nonalcoholic fatty liver (NAFL) yet it is a very common condition. If NAFL is not addressed, it can progress to a serious condition known as Nonalcoholic fatty liver disease (NAFLD) Non-alcoholic fatty liver is the buildup of extra fat in liver cells that is not caused by alcohol. It is normal for the liver to contain some fat. However, if more than 5% -10% percent of ...
By Algatech
-
Exploring the Intricate Link Between Bile Acids and Disease
Bile acids are synthesized in the liver from cholesterol as a raw material. As a natural "emulsifier", they can promote the dissolution, digestion and absorption of fats, fat-soluble vitamins, etc. Meanwhile, as an important signaling molecule, bile acids can activate the relevant receptors to maintain the homeostasis of hepatic glucose and lipid metabolism, and interact with gut bacteria to ...
-
Glucose Clamp Technique: Types & Applications
Glucose clamping has become a standard, widely used technique in researching diabetes treatment as well as obesity and fatty liver studies. We've taken a look at the types and applications of clamp study and their impact on the field. The Glucose clamp technique was first developed in 1979 by professors at the UT School of Medicine: DeFronzo, Andres and Tobin as a method of measuring insulin ...
-
How treatment of homes for termites decades ago may cause diabetes today
Obesity has been accepted as a risk factor for diabetes but results of four recently published studies have now revealed that insecticides in fat of patients may be the real risk factor. The initial investigations showed that the expected association between obesity and diabetes/insulin resistance was absent in people who had low levels of organochlorine insecticides in their blood (1, 2). ...
-
Cellular and molecular differences between HFpEF and HFrEF
Heart failure affects about 6.2 million Americans and is rising in prevalence. With half of these cases presenting as heart failure with preserved ejection fraction (HFpEF), it’s essential for both the medical community and the population at large to have a better understanding of its pathology. [1,2] Knowing the differences between HFpEF and its counterpart, heart failure with reduced ...
-
Research Progress of Tetrahydrocurcumin
Tetrahydrocurcumin (THC), as the most active and main metabolite produced in the metabolism of curcumin in vivo, can be isolated from the cytoplasm of the small intestine and liver after curcumin administration in human or mouse. Tetrahydrocurcumin can effectively inhibit tyrosinase, inhibit the generation of Oxygen Free Radicals and scavenge the formed free radicals. It has obvious antioxidant ...
Need help finding the right suppliers? Try XPRT Sourcing. Let the XPRTs do the work for you