diagnostic clinic Articles
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Multi-Site veterinary diagnostic laboratory uses Matrix Gemini LIMS for Seamless sample management case study
The Matrix Gemini Laboratory Information System (LIMS) from Autoscribe Informatics has been used to co-ordinate sample tracking, management and reporting across four different locations for a busy veterinary diagnostic and clinical pathology laboratory. Background Nationwide Laboratory Services Is a UKAS accredited independent multi-disciplinary veterinary laboratory providing diagnostic and ...
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Case Study B - Liquid Biopsy
X-ZELL is collaborating with Singapore General Hospital (SGH) and the National University Hospital Singapore (NUH) to explore how X-ZELL single-cell diagnostics may aid in the early detection of clinically significant prostate cancer in whole blood. The prospectively blinded, 400-patient multi-centre study officially commenced in 2020 and will lay the foundation for the launch of a commercially ...
By X-Zell Inc.
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The impact of variability in the risk of disease exemplified by diagnosing diabetes mellitus based on ADA and WHO criteria as gold standard
The diagnosis of clinically mute diabetes mellitus (DM) is based on a nominal concentration of fasting peripheral venous plasma glucose (f-vPG) at ≥7.0mmol/l, to be exceeded by first and confirmatory measurement. Aim: to identify error sources in the clinical use of biochemical data, to use the diagnostic concept for clinically mute DM. Materials and methods: error contributors were established. ...
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Enzymes Used for Producing Homocysteine Assay Kit: Unlocking the Secrets of Homocysteine Detection
Homocysteine, an important biomarker in the field of clinical diagnostics, plays a significant role in assessing cardiovascular disease risk, vitamin deficiencies, and genetic disorders. Accurate and sensitive detection of homocysteine levels is crucial for early intervention and personalized patient care. In this article, we delve into the fascinating world of enzymes for producing the ...
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Mid-Size Laboratories Can Now Enjoy the Same Efficiency Benefits as Large Facilities with Beckman Coulter’s New Hematology Analyzer
Beckman Coulter , a global leader in clinical diagnostics, today announced the commercial launch of its new DxH 690T hematology analyzer. Designed to help laboratories streamline workflow and maximize uptime, the DxH 690T offers all the benefits of the company’s flagship DxH 900 hematology analyzer to mid-size labs, including an industry-leading 93% first-pass yield and the recently ...
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INOVIQ (ASX:IIQ) signs agreement with Nicoya Lifesciences to develop SubB2M-based test
INOVIQ (IIQ) signs a contract research agreement with Nicoya Lifesciences to develop a SubB2M-based test that uses its Alto digital surface plasmon resonance (SPR) platform The company believes a SubB2M-based SPR test has the potential to be developed as a multi-cancer detection test that first detects the Neu5Gc cancer signal Under the agreement, INOVIQ will pay an agreed cost for the work ...
By INOVIQ Ltd
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Nature: Structure-based classification of tauopathies
Abnormal accumulation of misfolded tau in filaments is characteristic of many neurodegenerative diseases—precisely for this reason, these neurodegenerative diseases are collectively referred to as tauopathy. The Michel Goedert team and the Sjors Scheres team at the Molecular Biology Laboratory of the Medical Research Council in Cambridge, UK, witnessed the use of cryo-EM to dissect tau ...
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Significance of Diagnostic Enzyme Detection
Serum enzyme tests have been used in clinical practice for a long time, such as increased amylase activity in serum and urine of patients with acute pancreatitis. In the 1930s, some scholars reported that the determination of serum lipase and alkaline phosphatase activities is helpful for the diagnosis of pancreatitis and bone diseases, respectively. After the 1950s, the application of serum ...
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Application of Enzyme Detection in Clinical Diagnosis
Serum enzyme tests have been used in clinical practice for a long time, such as increased amylase activity in serum and urine of patients with acute pancreatitis. In the 1930s, some scholars reported that the determination of serum lipase and alkaline phosphatase activities is helpful for the diagnosis of pancreatitis and bone diseases, respectively. After the 1950s, the application of serum ...
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Calypso Released on UDN Data
We are excited to announce a beta release of our Calypso tool on the latest Phase II Undiagnosed Diseases Network (UDN) data. This is a project performed in collaboration with the UDN, and we encourage our initial set of UDN investigators to trial this release and provide any feedback, comments, questions or requests to info@frameshit.io. ...
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Teleradiology in Covid-19
The start of coronavirus pandemic pushed limits of healthcare systems all over the world by causing thousands of deaths and the requirement of a huge quantity of healthcare resources. When WHO declared COVID19 as a pandemic, the whole world came to standstill. Half of the world population is confined to their home except for essential services. In the year 2016, when GOI announced ...
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SNP Array, A Powerful Tool for Diagnosis and Agrigenomics Research
Single-nucleotide polymorphisms (SNPs) are a kind of DNA polymorphisms caused by single-nucleotide variants in both coding and non-coding regions, which are the most common and smallest variants. There are more than 3 million SNPs in the human genome with an average of 1 in 500-1000 base pairs. SNP microarrays are capable of detecting a large number of subtle DNA alterations and/or abnormal ...
By CD Genomics
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Monlab SL uses iPeak+ to obtain rapid results in drug testing
Monlab SL is a company dedicated to the service of the clinical diagnostic laboratory. They are providing a service according to the needs of hospitals, faculties, research centers, and clinical analysis. One of their business units is the marketing of reliable individual and multipanel blood and urine lateral flow tests. Monlab SL was looking for a reader that would analyze their lateral flow ...
By IUL S.A.
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What is the ICD code for HFpEF?
Heart failure with preserved ejection fraction (HFpEF) is currently affecting over half of heart failure patients. The Centers for Medicare and Medicaid Services (CMS) and the National Center for Health Statistics (NCHS), two departments within the U.S. Federal Government’s Department of Health and Human Services (DHHS), use the International Classification of Diseases (ICD) for coding ...
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Protein N-Glycosylation Analysis Strategy and Procedures
The glycan chain is located in the outermost layer of the cell and is the first molecule encountered and recognized by other cells, antibodies, invading viruses and bacteria. N-glycans regulate a wide range of cellular functions, including cell-cell and cell-matrix adhesion, cell proliferation, cell survival and immune system response, by affecting protein folding, recognition, clearance, ...
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Adoption of medical technology by hospitals: a review of innovation attributes and a conceptual model of the resulting service
Innovative medical technologies help to transform health care by empowering physicians and patients with tools that enable faster diagnosis and better treatment of disease. Diagnostic practices and procedural functions in clinics and surgeries are dependent on modern instruments, tools and laboratory equipment. This paper examines innovation attributes in detail and discusses their implications ...
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Cytokines: Characteristics, Applications, and Quantitative Analysis
Cytokines represent a class of small protein molecules that exhibit diverse biological activities. These molecules are synthesized and secreted primarily by immune cells (including monocytes, macrophages, T cells, B cells, and NK cells) as well as certain non-immune cells (such as endothelial cells, epidermal cells, and fibroblasts) upon specific stimulation. Cytokines play pivotal roles in ...
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Nuclea Launches Strategic Partnership with Aelan in Field of Epigenetics
CAMBRIDGE, MA--(Marketwired - Jun 30, 2015) - Nuclea Biotechnologies Inc. announced today that it is partnering with Aelan Cell Technologies Inc. (San Francisco, California) for the development, validation and commercialization of novel biomarker tests and companion diagnostics using human STEM cells as models. Their collaboration has the potential to impact disease monitoring and drug ...
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Maternal serum glycosylated fibronectin as a short-term predictor of preeclampsia: a prospective cohort study
Abstract Background: Preeclampsia is a major pregnancy complication that results in significant maternal and infant mortality, most of which occurs in low and middle-income countries. The accurate and timely diagnosis of preeclampsia is critical in management of affected pregnancies to reduce maternal and fetal/neonatal morbidity and mortality, yet difficulties remain in establishing the rigorous ...
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Diagnosing heart failure with preserved ejection fraction (HFpEF)
Heart failure with preserved ejection fraction (HFpEF) has recently been recognized as the single greatest unmet need in cardiovascular medicine, overtaking heart failure with reduced ejection fraction (HFrEF) and becoming the most common form of heart failure, with a prevalence that is increasing by 1% annually.[1] Despite this, there remains no gold standard in diagnosing HFpEF. Diagnosing ...
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