disease free Articles
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Generating a robust prediction model for stage I lung adenocarcinoma recurrence after surgical resection
Abstract Lung cancer mortality remains high even after successful resection. Adjuvant treatment benefits stage II and III patients, but not stage I patients, and most studies fail to predict recurrence in stage I patients. Our study included 211 lung adenocarcinoma patients (stages I–IIIA; 81% stage I) who received curative resections at Taipei Veterans General Hospital between January ...
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The development of complete personalized treatment plans for colon cancer patients utilizing three gene prediction models.
Background Combination chemotherapy using fluorouracil, leucovorin with or without oxaliplatin (5-FU and FOLFOX) are standard treatment for locally advanced colon cancer. However, about half of the patients developed recurrence. The objective of this study was to use gene profiling to predict treatment efficacy for colon cancer patients (stages 1-3). We developed three prediction models: the ...
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Infrared spectroscopy of human bone marrow: evidence of structural changes during acute leukemia
Fourier transform infrared (FTIR) spectroscopy was explored as a means to distinguish newly diagnosed of acute lymphoblastic leukemia from disease free bone marrow samples. Characteristic bands alterations were identified in both healthy and diseased samples arising from cellular protein, lipid and DNA. There were specific changes that affected the secondary structure of proteins that appeared in ...
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A comparative study of antioxidant activity between black tea from Rwandan highlands with green and oolong teas from China
Antioxidant activity of the aqueous extract of black tea from Rwandan highlands was compared with that of green and oolong teas from China and was determined by use of 2, 2-diphenyl-1-picrylhydryzyl (DPPH) radical scavenging method. The higher the concentration of the extract, the higher was free radical scavenging activity. Antioxidant activity of the teas extracts decreased in the order: green ...
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A new model using artificial intelligence to predict recurrence after surgical resection of stage I-II non-small cell lung cancer.
Abstract Background: Five-year survival for stage I-II lung cancer is quite low even after complete surgical resection. Current guidelines recommend adjuvant treatment only for selected patients with stage II or higher disease. A prediction model that identifies patients at high risk of recurrence who may benefit from adjuvant treatment is greatly needed. Many existing prediction models include ...
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Comparison of genomic signatures of non-small cell lung cancer recurrence between two microarray platforms
Abstract Background Cancer genomic signatures may vary using different platforms. We compared the differential gene expression in non-small cell lung cancer (NSCLC) between two platforms in order to find the most relevant genomic signatures of tumor recurrence. Materials and Methods We analyzed gene expression in frozen lung cancer tissue from 59 selected patients who had undergone surgical ...
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Under Sewer-Veillance - Wastewater & COVID-19
Wastewater & COVID-19 Connections When the word wastewater crosses your mind, there is probably also a memory of your Mom’s voice telling you – wash your hands! When humans transitioned into community living, keeping your living space separate from your bathroom space was an important rule to learn. We can thank early scientists who were curious about how diseases spread and ...
By Flottweg SE
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Intraoperative Radiation Therapy (IORT) with VeraForm: Marking for Variability
Radiation therapy choices vary for comprehensive breast cancer treatment. One such option, intraoperative radiation therapy (IORT) is employed in many centers around the country. IORT using the Zeiss® Intrabeam® System has been proven to be non-inferior to External Beam Radiation Therapy (EBRT) in local recurrence and disease-free survival. IORT’s advantage is one treatment during ...
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Fatty Acids in Cancer
Fatty acids, along with glucose and amino acids, are the main source of energy for cell growth and proliferation. Abnormalities in fatty acid metabolism are commonly seen in cancer. A growing number of studies have shown that increased ab initio synthesis of fatty acids in tumor cells is a prominent feature in the development of cancer. And the activation of ab initio synthesis is negatively ...
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How Has the COVID-19 Pandemic Affected Prostate Cancer Care?
#CancelEverything On March 11, 2020, the World Health Organization (WHO) declared the coronavirus 2019 disease (COVID-19) a global pandemic. Its impact left the world uncertain about health, politics and the economy. The first wave caused a major disruption to health services, exacerbating concerns of patient and physician safety and resource availability. On trend with the “cancel ...
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The Importance of Surgical and Medical Asepsis
It goes without saying that when entering a hospital, it is expected that the hospital is clean, sterile, and both patients and the healthcare workers are protected from harmful contamination. To accomplish this level of cleanliness, medical professionals follow a strict series of practices and procedures known as the aseptic technique. Correctly implemented, this technique creates conditions ...
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The Function and Application of the Magic Superoxide Dismutase
Some substances can easily interact with the oxygen in the air when exposed to the air, causing chemical changes in the substance. This is the process of oxidation. Sun exposure, air pollution, radiation, etc. will cause the human skin to produce a large amount of superoxide free radicals, and its strong oxidizing ability will accelerate the speed of skin oxidation, and may even cause serious ...
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Foundational Supplement Program with Whole Food AstaPure® Arava
One of the most pressing questions consumers have is, "What supplements do I need to take daily?" The answer should be simple, start with a strong foundation. Just as if you were building a home, you would first pour a strong foundation in which to build on. The same holds with taking dietary supplements. The four areas of supplementation consumers need fall into these categories: Antioxidant(s), ...
By Algatech
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