Disease Ibd Articles & Analysis: Older
11 articles found
Moreover, TREM1 activation augments the oxidative burst and microbicidal activity of phagocytes, illustrating its role in host defense mechanisms. Implications in Disease The dysregulation of TREM1 has been implicated in an array of inflammatory and infectious diseases. ...
These mRNA-loaded LNPs deliver specific mRNA to the liver for the treatment of various liver-related diseases, including infectious diseases, liver fibrosis, cancer, and genetic disorders. 2) Spleen or lung targeting LNP: Researchers at the University of Texas Southwestern Medical Center reported that selective organ targeting capability can be achieved by ...
Cytokine Dysregulation in Systemic Immune Diseases The perturbation of immune tolerance leads to disruption in cytokine homeostasis. ...
In addition to being a target for skin inflammatory diseases, IL-36 can also be an effective drug target for inflammatory bowel disease (IBD), rheumatoid arthritis, and other inflammatory diseases. ...
Application in the diagnosis and prognosis determination of small intestinal clonorchiasis Small bowel clonorchiasis is an inflammatory disease of the intestine of unknown origin. It and chronic non-specific ulcerative colitis are collectively known as inflammatory bowel disease (IBD). The disease is active with shortening and ...
Furthermore, TNF-a represents the most validated clinical target for ulcerative colitis (UC) and inflammatory bowel diseases (IBD) with multiple emerging neutralizing/inflammation-reducing therapeutics targeting this cytokine for inactivation. ...
Observational study with retrospective and prospective data collection, for total of 24 months. This is an IBD technology study investigating quantitative metrics for endoscopy, histology and radiology for improved diagnosis and assessment of ...
Key questions in intestinal health and disease require an understanding of how changes in intestinal niches cause, perpetuate, or allow recovery from injury. ...
With access to a donor-derived cell biobank and the ability to recapitulate region-specific environments of the intestine, Altis Biosystems is working toward the development of an in vitro RepliGut® model to accurately recapitulate the complex intestinal inflammatory microenvironments. Inflammatory Gut Diseases are Complex Inflammation is a key factor in many intestinal ...
Abstract Gut microbiota play a major role in host physiology and immunity. Inflammatory bowel diseases (IBDs), the important immune-related diseases, can occur through immune system malfunction originating due to dysregulation of the gut microbiota. ...
Bio-Me is one of the participants in a new Nordic project that will develop personalized treatment for IBD patients. In December 2018, the Nordic Council’s research department awarded Nordfors 30 million for a research project with the theme of personalized medicine for inflammatory bowel disease (IBD). The study has been titled ...
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