Disease On Economic Development Articles & Analysis: This-Year
9 articles found
Introduction The BALB/C mouse is a widely used inbred strain in biomedical research, particularly in the fields of immunology, cancer research, and genetics. Among the various tissues studied, the kidney holds significant importance due to its complex structure and multifaceted role in physiological functions. A formalin-fixed paraffin-embedded (FFPE) block of the BALB/C mouse kidney serves as an ...
Matrix Gla Protein (MGP) is a small, vitamin K-dependent extracellular matrix protein that plays a critical role in the regulation of vascular calcification and bone development. As a natural inhibitor of pathological mineralization, MGP has attracted significant attention in cardiovascular and skeletal biology research. The development of recombinant MGP protein has enabled researchers to study ...
Tissue cross-reactivity studies play an essential role in the understanding of immune responses, particularly in the context of autoimmunity, transplant rejection, and vaccine development. These studies aim to identify whether antibodies or T cells generated against a particular antigen react with similar proteins found in different tissues, which can lead to unintended effects and complications. ...
Histological image analysis has emerged as a pivotal domain in biomedical research and clinical diagnostics, allowing scientists and healthcare professionals to decipher the intricate structures of tissues at a microscopic level. This analysis encompasses the examination of biological tissues to understand their composition, organization, and pathology, which can be crucial for diagnosing ...
Cytokines are small proteins that play a crucial role in cell signaling, particularly in the immune system. They regulate inflammation, immunity, and hematopoiesis, making them essential for understanding various biological processes and disease mechanisms. For researchers working with rabbit models, the ability to accurately measure cytokine levels is vital. This is where Customized Rabbit ...
The cell cycle is an essential biological process that enables cells to grow, duplicate their DNA, and divide into daughter cells. This cycle is carefully regulated by proteins to ensure accuracy in cell replication. Disruptions in these controls can lead to uncontrolled cell division, a hallmark of cancer and other diseases. Cell cycle progression is orchestrated by key proteins, including ...
Nuclear receptors are a class of proteins that play a vital role in cellular communication, gene expression, and overall homeostasis within the body. They act as transcription factors, responding to various stimuli, including hormones, nutrients, and even environmental agents. Due to their crucial roles in physiological and pathological processes, nuclear receptors have emerged as significant ...
Non-alcoholic fatty liver disease (NAFLD) has emerged as a significant public health concern, associated with obesity, insulin resistance, and a spectrum of metabolic disorders. Understanding this condition is crucial for effective intervention and treatment. Preclinical models are indispensable for advancing our knowledge of NAFLD, as they provide the necessary platforms to study its ...
Colorectal cancer is one of the leading causes of cancer-related deaths globally. To advance our understanding of this disease and improve treatment strategies, researchers heavily rely on colorectal cancer cell lines. These cell lines serve as essential models for studying the biology of colorectal cancer, testing new therapies, and exploring the mechanisms of drug resistance. What are ...