disease research Articles
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Genetic tools for select-agent-compliant manipulation of burkholderia pseudomallei
Department of Microbiology, Immunology and Pathology, Rocky Mountain Regional Center of Excellence for Biodefense and Emerging Infectious Diseases Research, Colorado State University, Fort Collins, Colorado 80523-1682, and School of Medical Science and Institute for Glycomics, Griffith University—Gold Coast Campus, Gold Coast, Queensland 9726, ...
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What Are the Applications of Enzymes in Disease Research and Treatment?
With the development of biotechnology in the modern information age, the research, development and utilization of enzymes have become more and more in-depth, and correspondingly, the application of enzymes in medicine has become more and more extensive. 1. The relationship between enzymes and certain diseases The diseases caused by the lack of enzymes in the human body are mostly congenital or ...
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US armed forces medical operations other than war
Expertise in combat healthcare planning, operations and technology translates well into domestic and international humanitarian health relief. The US military medical services have extensive daily activities in public health and medicine that are integrated with civilian organisations, and are related to health research, prevention of disease and healthcare rather than to combat operations. These ...
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CD Genomics Perspective: RNA Sequencing, A Powerful Method for Studying Various Diseases
Although post-mortem brains have been frequently reported as the "gold standard" in transcriptomic research for ND and neuropsychiatric abnormalities, the main sources has been mRNA separated from transgenic animal models and, more lately, patient-derived cell lines. However, despite their promise, transcriptome studies are difficult due to the obvious difficulties in obtaining brain tissue and ...
By CD Genomics
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New Breakthrough in Cancer Cell Research
The body's immune system is an effective weapon against disease, and immunotherapy of cancer cell research is the current frontier in the treatment of cancer and other diseases. Recently, researchers at Notre Dame University have identified specific features of the reaction of two distinct peptide antigens to a T-cell receptor (TCR), which provides new clues to optimizing molecular structure ...
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Development of Gene Therapy Viral Vectors for Rare Diseases
In many cases, gene therapy requires a vector to deliver the gene therapy drug to the target cell. Viral vectors have been one of the most widely studied vectors due to their outstanding transduction efficiency and other significant advantages. Viral vector-based gene therapy has now achieved good clinical results. More than a dozen viral gene therapy products have been approved for the treatment ...
By Protheragen
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HealthySole launches UVC-powered shoe sanitizer for healthcare settings
HealtySOLE has launched a new PLUS model of its shoe sanitizer meant for use in hospitals and other settings where infection control is urgent. Researchers have proven a device using ultraviolet light technology can neutralize the coronavirus and other infectious diseases on the soles of shoes by more than 99.5 percent, according to a new study. “The device deactivated coronavirus ...
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Bioinformatics Analysis Brings Disease Genomics Research to a Crossroads
Introduction Since the completion of the Human Genome Project, genomics has played an increasingly critical role in the biomedical field. Its applications include variation and risk assessment in disease genomics, analysis of changes in transcriptomic gene expression, revealing epigenetic effects on tissue and organ development, and heterogeneity at the single-cell level, among others. We present ...
By CD Genomics
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MC3R Links Nutritional Status to Child Growth and Pubertal Timing
Scientists have determined how a protein in the brain uses information about the body's energy balance to regulate children's growth rate and the onset of puberty. The study focuses on the melanocortin 3 receptor (MC3R), a member of the protein family, which has long been thought to play an important role in metabolism and energy balance. Roger Cone, a physiologist at the University of ...
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Whole Genome Sequencing for Rare Diseases
The diagnosis and treatment of rare diseases have long been a daunting challenge due to their complex and often undefined nature. However, with recent advancements in technology, specifically in the realm of genomics, whole genome sequencing (WGS) has emerged as a powerful tool that has revolutionized the diagnosis and management of rare diseases. This groundbreaking technique offers hope to ...
By Protheragen
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Longevity in Nepal: health, policy and service provision challenges
Longevity is a relatively recent phenomenon in Nepal; over the past few decades the priority in Nepal has been reducing infant and maternal mortality. With an increasingly ageing population and changing patterns of migration, this brings with it challenges to Nepali society in terms of meeting the needs of an ageing population and creating a policy environment that ensures these needs are met. ...
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A Closer Look at Reporter Lentiviral Particles: Tool for Biomedical Research
Introduction For years, scientists have leveraged the brilliant potentialities of genetic science to explore how cells function and interact in living organisms. Among the numerous tools employed are "reporter systems," which use a visible marker to track gene expression, protein interactions, and other vital biological processes. One such system employs reporter lentiviral particles, using the ...
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Financials keeping the local market in the green: ASX up 0.51% at noon
Financials have been keeping the ASX in positive territory in today’s session, following improved sentiment for financial stocks after the Bank of Queensland (ASX:BOQ) yesterday announced better-than-expected Net Interest Margin performance. This has bolstered financial stocks and the broader market. At noon, the S&P/ASX 200 is 0.51 per cent or 34.10 points higher at 6681.60. The SPI ...
By INOVIQ Ltd
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How the Breuer Lab tracks their sample information at every step of their research
Dr. Eun-Kyoung Breuer is an Assistant Professor and an Associate Director of the Radiobiology Program in the Department of Radiation Oncology at Loyola University Chicago. Her lab's research focuses on understanding the role that tumor suppressor genes play in the DNA damage response pathway and in breast cancer regulation. A centralized information management approach Doing research focuses on ...
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What is Label-Free Quantification Technique?
The protein label-free quantification technique analyzes protein enzymatic peptide fragments by liquid-quality coupling and compares the signal intensity of the corresponding peptide fragments in different samples for relative quantification of the protein. This method is not dependent on isotope labeling and does not require expensive stable isotope labels as internal reference. The technique is ...
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Applications of Microbial Whole Genome Sequencing
Microorganisms widely exist in nature and are closely related to human life and production. They are generally divided into fungi, actinomycetes, bacteria, spirulina, rickettsia, chlamydia, mycoplasma and viruses. Microbial whole genome sequencing is an important tool for mapping genomes of novel organisms, finishing genomes of known organisms, or comparing genomes across multiple samples. ...
By CD Genomics
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CD Genomics Perspective: High-Throughput Sequencing Approach to Explore the Human Microbiome
The Use of Microbiome Sequencing in Cancer Research A growing body of evidence now suggests that human microbial dysbiosis has a crucial role in cancer development and progression. Unlike earlier studies relying on culturing bacteria from the tissue of cancer, high-throughput sequencing methods have enabled genotyping the microbial ecosystem within cancer tissue from hundreds to thousands of ...
By CD Genomics
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AMPK Signaling Pathway and Function
AMPK (Adenosine 5'-monophosphate (AMP)-activated protein kinase), as an important kinase regulating energy homeostasis, is one of the central regulators of eukaryotic cell and organism metabolism. It is responsible for regulating cellular capacity input and output and maintaining the smooth functioning of cellular physiological activities. AMPK is also a key protein involved in various signaling ...
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Flu shots urged as Madison’s FluGen plays role in effort for universal vaccine
David Wahlberg, Wisconsin State Journal October 18, 2018 With flu season approaching, health officials say people should get flu shots by the end of October, yet acknowledge that the annual vaccine generally works less than 60 percent of the time. The Madison company FluGen is part of a renewed national effort to improve the odds by developing a universal flu vaccine, which would protect ...
By FluGen, Inc.
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New Findings about Capsular polysaccharide You May Want to Know
Streptococcus pneumoniae is the leading cause of pneumonia, sepsis and meningitis. Collectively, these infections are a leading cause of morbidity and mortality in older adults and young children. To fight these deadly infections, a pneumococcal vaccine is given to stimulate the production of antibodies against CPS. However, bacteria can manipulate their CPS structure to evade these antibodies. ...
By CD BioGlyco.
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