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Disease Risk Articles & Analysis

49 articles found

Cardiovascular Biology: Latest Research and Innovations

Cardiovascular Biology: Latest Research and Innovations

This finding underscores the need to reduce plastic usage, especially with hot foods, to minimize health risks. 2. A New Drug to Reduce Heart Attacks and Strokes The newly approved drug Sotagliflozin (Inpefa) has shown promise in reducing heart attacks and strokes among patients with type 2 diabetes and chronic kidney disease. ...

ByCreative BioMart


How Predictive Analytics is Boosting Clinical Trials Efficiency?

How Predictive Analytics is Boosting Clinical Trials Efficiency?

Clinical trials are the backbone of modern medicine, responsible for bringing innovative, safe, and efficient treatments to market after rigorous testing and evaluation. However, the conventional process of conducting these trials has often been long, expensive, and fraught with inefficiencies¹. The advent of predictive analytics is reshaping the landscape of clinical trials, ushering in a ...

BySOPHiA Genetics


Matched tumor-normal sequencing: The preferred method for identifying somatic mutations driving tumorigenesis

Matched tumor-normal sequencing: The preferred method for identifying somatic mutations driving tumorigenesis

Discover how matched tumor-normal sequencing can help clinical researchers detect the somatic origin of variants with certainty. In the era of precision oncology, it has become increasingly common for patients diagnosed with cancer to undergo tumor sequencing. Identifying the mutations that make up a tumor’s genomic landscape can help guide selection of targeted therapies and inform ...

BySOPHiA Genetics


Will Metformin Be Replaced By SGLT-2 Inhibitors

Will Metformin Be Replaced By SGLT-2 Inhibitors

GLP-1 agonists and SGLT-2 inhibitors in combination with or without metformin (as required for glycemic management) have also been recommended by multiple guidelines as appropriate initial treatment for type 2 diabetes patients with atherosclerotic cardiovascular disease (ASCVD) or those at high risk for ASCVD, heart failure and/or chronic kidney ...

ByHunan Huateng Pharmaceutical Co. Ltd.


Corey’s Story: First Patient Treated with BEAR® Implant Going Strong After Six Years

Corey’s Story: First Patient Treated with BEAR® Implant Going Strong After Six Years

Owens notes that the harvesting of a healthy tendon can sometimes result in kneeling pain or reduced strength in the hamstring or quad muscles, to name some of the possible side effects. There is also a risk of disease transmission when using donor tissue. “Surgeons have always been interested in healing the ACL, but the technology to do so did not ...

ByMiach Orthopaedics, Inc.


Luna’s Story: Teen Trailblazer Becomes First BEAR Implant Patient in Connecticut

Luna’s Story: Teen Trailblazer Becomes First BEAR Implant Patient in Connecticut

However, short- and long- term side effects are possible with this reconstructive procedure, including pain when kneeling, reduced strength in the hamstring or quad muscles and a possible risk of disease transmission when donor tissue is used. Unlike many other ligaments in the body, the ACL does not have the natural ability to heal on its own. ...

ByMiach Orthopaedics, Inc.


Phoebe’s Story: A Cross-Country Journey to Repair a Torn ACL

Phoebe’s Story: A Cross-Country Journey to Repair a Torn ACL

Replacing the torn ligament through ACL reconstruction is the most common treatment for this injury but can sometimes result in side effects such as pain when kneeling, reduced strength in the hamstring or quad muscles, and the risk of disease transmission when donor tissue is used. There is also an increased concern of developing long-term arthritis. ...

ByMiach Orthopaedics, Inc.


Clinician Attitudes are Shifting on MRD-guided Decision Making in Multiple Myeloma

Clinician Attitudes are Shifting on MRD-guided Decision Making in Multiple Myeloma

This September marks four years since the 2018 Food and Drug Administration clearance for clonoSEQ to detect and monitor minimal residual disease (MRD) in bone marrow from patients with acute lymphoblastic leukemia (ALL) and multiple myeloma (MM). ...

ByAdaptive Biotechnologies


Nanostics Receives CE Mark for its ClarityDX Prostate Test to Detect Clinically Significant Prostate Cancer

Nanostics Receives CE Mark for its ClarityDX Prostate Test to Detect Clinically Significant Prostate Cancer

The ClarityDX Prostate® test uses a proprietary machine-learning algorithm that combines data from biological and clinical biomarkers to generate a risk score for clinically significant prostate cancer, defined as Gleason grade group 2 or higher, on prostate biopsy. ...

ByNanostics Inc.


Nanostics Announces Study Data Supporting ClarityDX Prostate as a Reflex Test to Predict Clinically Significant Prostate Cancer

Nanostics Announces Study Data Supporting ClarityDX Prostate as a Reflex Test to Predict Clinically Significant Prostate Cancer

EDMONTON, AB, June 30, 2022 /CNW/ - Nanostics Inc., a precision health diagnostics company, today announces positive data from a pre-biopsy clinical validation study of its ClarityDX Prostate® test designed to improve the accuracy of detecting clinically significant prostate cancer in men that are at risk of the disease. The ClarityDX Prostate® test uses ...

ByNanostics Inc.


Nanostics Announces the Launch of its Bladder Cancer Clinical Study Identifying Disease Predictors for Early Detection of Bladder Cancer

Nanostics Announces the Launch of its Bladder Cancer Clinical Study Identifying Disease Predictors for Early Detection of Bladder Cancer

Nanostics’ ClarityDX Bladder test uses extracellular vesicle detection technology and machine-learning model analysis to identify the most potent disease predictors for the early detection of bladder cancer. “Strategic investments in digital health are enabling Alberta to become more globally competitive towards increasing health and economic benefits for our ...

ByNanostics Inc.


Inflammation in Periodontal Disease a Red Flag for Cancer

Inflammation in Periodontal Disease a Red Flag for Cancer

Even moderate gum disease contributed an increased risk of cancer, including blood, kidney and lung cancers in smokers as well as non-smokers. Risk of Kidney Cancer, Leukemia and Lung Cancer Increase with Gum Disease An American and British research team at Harvard University and the Imperial College in London examined the ...

ByDental Air Force Labs


Link Between Periodontal Disease and Oral Cancer

Link Between Periodontal Disease and Oral Cancer

Recent Study Concludes that Periodontitis was Associated with Tongue Cancer In a recent study, the gum disease periodontitis was associated with an increased risk of developing tongue cancer. ...

ByDental Air Force Labs


SNP Array, A Powerful Tool for Diagnosis and Agrigenomics Research

SNP Array, A Powerful Tool for Diagnosis and Agrigenomics Research

SNP Array in Clinical Diagnosis Accurate identification and definition of genome aberrations can influence classifications of disease, patient risk stratification and clinical management options for a variety of genetic diseases, such as tumors. ...

ByCD Genomics


Breakdown of How Sugar Impacts The Brain and Cognitive Function

Breakdown of How Sugar Impacts The Brain and Cognitive Function

Below, we break down how sugar impacts the brain, including its effect on cognitive function, mood, and disease risk. ...

ByAltoida, Inc.


The Link Between Smoking and Cognitive Decline

The Link Between Smoking and Cognitive Decline

By now, you are likely aware of many of the well-established risks associated with smoking cigarettes, such as cancer, asthma, chronic obstructive pulmonary disease (COPD), diabetes, cardiovascular disease, and stroke. ...

ByAltoida, Inc.


Novel Biomarkers May Help Predict the Susceptibility of a Population to Rheumatoid Arthritis

Novel Biomarkers May Help Predict the Susceptibility of a Population to Rheumatoid Arthritis

Genetics (i.e., mutations) are considered to be the main factor predisposing to the etiology of rheumatoid arthritis (RA), but they account for only a few changes in RA disease risk, and in contrast to genetics, the environment may have an important impact on epigenetic properties associated with disease etiology. ...

ByCreative BioMart


CD Genomics Perspective: The Application of RNA-Seq and DNA-Seq in Cancer Research

CD Genomics Perspective: The Application of RNA-Seq and DNA-Seq in Cancer Research

Human DNA sequences are 99.9% identical; the 0.1 percent variance accounting for changes in illness risk from one person to the next. Rapid advances in DNA sequencing technology and bioinformatics (the ability to store and assess large databases of genomic data) have allowed us to identify and catalog DNA variations, as well as evaluate which variants (changes in DNA sequence, ...

ByCD Genomics


Landmark study confirms that controlled blood pressure is key to prevent stroke, heart disease

Landmark study confirms that controlled blood pressure is key to prevent stroke, heart disease

Follow-up data from the landmark SPRINT study of the effect of high blood pressure on cardiovascular disease have confirmed that aggressive blood pressure management — lowering systolic blood pressure to less than 120 mm Hg — dramatically reduces the risk of heart disease, stroke, and death from these ...

ByCardiox Corporation


How Is the COVID-19 Virus Transmitted?

How Is the COVID-19 Virus Transmitted?

15 weeks into the COVID-19 pandemic, scientists know a lot more about how the disease is transmitted. The highest risk for public health is from crowded indoor spaces with poor ventilation, and especially with prolonged face-to-face interactions. ...

ByAirora, Division of Hydroxyl Technologies

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