Drug Application Articles & Analysis
46 articles found
This transformation enables them to differentiate into any cell type, offering significant potential for disease modeling, drug discovery, and therapeutic applications. However, proper characterization of iPSCs is critical to ensuring their utility and safety in research and clinical settings. ...
Chemical synthesis is particularly beneficial for generating complex and modified lipids that may not be easily isolated from natural sources. One notable application of chemical synthesis is in the development of lipid conjugates used in drug delivery systems. ...
The MDCK permeability assay is a critical technique employed in pharmacology and drug development to evaluate the permeability of drug candidates across epithelial cell layers. ...
Watertown, MA – March 24, 2025 – Biopharma PEG, a leading supplier of high-quality polyethylene glycol (PEG) derivatives, highlights its innovative product DSPE-PEG-Mannose, an advanced biomedical polymer with significant potential in drug delivery, tumor-targeted therapy, tissue recognition, and adhesion.Structural Advantages of DSPE-PEG-MannoseDSPE-PEG-Mannose is composed of ...
In the rapidly evolving field of cellular biology and genetic engineering, the development of efficient and reliable cell lines is vital for research and therapeutic applications. One such advancement is the establishment of the Monkey DLL3 stable cell line using HEK293T cells. This article provides an overview of the significance of this cell line, its ...
They are FDA-approved and often used in various applications, from sutures to drug delivery systems. Similarly, PEG copolymers also boast high biocompatibility, as they are associated with a minimal immunogenic response. ...
Their unique chemical properties, such as reactivity and ability to form diverse structures, make them invaluable in drug synthesis and other industrial applications. This article delves into the chemical characteristics of phosphorus compounds, their applications in drug development, and their significance in enhancing ...
Absorption refers to how a drug is absorbed into the bloodstream after administration. Factors influencing this process include the drug’s solubility, chemical stability, and the route of administration. ...
Pharmaceutical Development: These cell lines are essential in the drug discovery pipeline, allowing for high-throughput screening and functional assays to evaluate drug efficacy and safety. Biotechnology Applications: Beyond disease research, knockin technologies are employed to create cell lines producing therapeutic proteins, monoclonal ...
Alfa Cytology has introduced its advanced drug development services for brain tumors. Alfa Cytology, celebrated for its cutting-edge biotech solutions and extensive tumor research expertise, has recently introduced brain tumor drug development services, designed to empower researchers in understanding the intricacies and unique challenges associated with brain ...
Antibody drugs are a type of drugs that treat diseases through artificially synthesized antibodies, which bind specifically to target molecules for therapeutic purposes. ...
Glycosylated impurities refer to a kind of glycosylated product formed during the synthesis, storage, and use of drugs, mainly resulting from non-enzymatic reactions between sugars and drug molecules. ...
They are currently a focus in new drug development. The design of antibody drugs is a complex and delicate process, and its success often depends on a deep understanding and precise analysis of the antibody itself. ...
Circular Dichroism (CD) uses the absorption properties of optically active substances to analyze the molecular structure of drugs. It has very valuable applications in drug analysis, including:1. ...
Antibody drugs, particularly monoclonal antibodies (mAb), play a critical role in the treatment of many diseases, especially in the treatment of cancer and immunological disorders. To ensure the effectiveness and safety of these antibody drugs, it is necessary to perform activity testing.Definition of Antibody ActivityThe activity of an antibody ...
They also have a high degree of stability and solubility, making them suitable for various routes of administration. One of the first applications of nanobodies in drug delivery was the development of targeted drug delivery systems. ...
They are essential in unraveling the molecular mechanisms underlying cell death and are instrumental in drug development, cancer research, and developmental biology. Types of Apoptosis Assays Morphological Assays: These assays examine the characteristic morphological changes that occur during apoptosis. ...
In addition, carboxylic acid PEGs can be involved in regulating interactions with cells, such as fusion with cell membranes and cellular uptake, providing effective carriers for cell therapy and gene delivery. Applications of PEGs and Carboxylic Acid PEGs Drug Delivery PEG and its carboxylic acid derivatives have important applications in ...
Microneedles have gained significant attention in recent years for their potential in drug delivery applications. These tiny needles, typically measuring less than 1 mm in length, can painlessly penetrate the skin and deliver drugs in a precise and controlled manner. ...
Inorganic Nanoparticles Functionalization Inorganic nanoparticles, such as gold or silver nanoparticles, have unique properties that make them suitable for drug delivery applications. These nanoparticles can be functionalized with targeting ligands or therapeutic agents to enhance their efficacy and specificity. ...