drug coated Articles
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The Function of Drug Coating
Coating refers to the unit operation of applying a layer of outer coating material to the dry surface of the formulation. This coating material not only makes the product easier to identify, but even improves the pharmacokinetic properties of the drug by altering its release: ensuring that the drug reaches its target and provides sufficient concentrations in the body to be maintained for an ...
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A novel, dual acting, soft pellet formulation, combining cushioning and rapid disintegration properties, and their incorporation into tablet formulations containing film-coated drug pellets
This work reports the concept of a novel, dual-acting, 'soft' pellet formulation, which protects film-coated 'hard' pellets during tabletting. The novel 'soft' pellets were designed to both cushion film-coated pellets during tabletting and ensure rapid disintegration of the tablets when in contact with water. The deformability and disintegration properties of these pellets were controlled using ...
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Alucent Biomedical Re-Envisioning PAD Treatment with a Natural Vascular Scaffold
Start-up Alucent Biomedical is using a light-activated molecule, delivered via a balloon catheter, to create a natural vascular scaffold in diseased peripheral vessels, with the aim of providing a long-lasting treatment option that maintains patency while leaving nothing behind in the vessel. Alucent Biomedical Inc. is rethinking peripheral artery disease (PAD) treatment with a novel natural ...
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Microneedle Patch Technologies: Innovations in Drug Delivery
Microneedle patch technologies have revolutionized the field of drug delivery, offering a wide range of advantages over traditional methods. These innovative patches provide a minimally invasive and painless alternative to injections while ensuring precise and controlled drug administration. In this article, we will explore various types of microneedle patch technologies, including ...
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3D Printing Technology for Microneedle Preparation
Microneedles have gained significant attention in recent years for their potential in drug delivery applications. These tiny needles, typically measuring less than 1 mm in length, can painlessly penetrate the skin and deliver drugs in a precise and controlled manner. One of the key challenges in microneedle fabrication is achieving high precision and uniformity in needle design, and this is where ...
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Philips to further expand its image-guided therapy devices portfolio through acquisition of Vesper Medical
Amsterdam, the Netherlands – Royal Philips (NYSE: PHG; AEX: PHIA), a global leader in health technology, today announced that it has signed an agreement to acquire Vesper Medical Inc., a US-based medical technology company that develops minimally-invasive peripheral vascular devices. Vesper Medical will further expand Philips’ portfolio of diagnostic and therapeutic devices ...
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What Is Drug Stability Analysis? - Basics You Need to Know in Drug Discovery
The basic requirements of pharmaceutical preparations are safety, efficacy, and stability. Drug stability means that a drug product should maintain the same properties and characteristics as it was at the time of production and within the specified time frame. The stability of pharmaceutical preparations directly affects the effectiveness and safety of drugs. Therefore, it is of great ...
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Exploring the Origins and Categorization of Microneedles
Microneedles (MN) is a new type of physical permeability-enhancing technology. It consists of multiple micron-scale fine needle tips connected to the base in an array. The needle body is generally 10-2000 microns high and 10-50 microns wide. The length, size and shape of the microneedles can be individually designed according to the needs of the application. When the microneedle delivers the ...
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Nanoparticulate systems for oral drug delivery to the colon
A review of oral drug delivery to the colon is a difficult but desirable method of administration. In order to target the colon the dosage form must overcome the barriers presented by the gastrointestinal tract including the steep pH gradient, binding to the mucus layer, premature clearance, and premature cellular uptake. Nanoparticles have been fabricated via a number of methods and designed ...
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Microneedle Patch Technology: Revolutionizing Drug Delivery
Introduction Advancements in medical technology have led to innovative solutions for various healthcare challenges. One breakthrough is microneedle patch technology, holding immense promise in revolutionizing drug delivery. These patches consist of micron-sized needles that painlessly penetrate the skin's outermost layer, enabling the controlled release of medications or therapeutic agents. In ...
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Preparation and characterisation of 5–fluorouracil containing PLGA nanospheres coated with chitosan, for drug delivery
The aim of this study was to design a new Drug Delivery System (DDS) based on poly (lactide–co–glycolide) (PLGA) biodegradable nanospheres (NS) coated with Chitosan (CTS), in order to prolong its residence time and to deliver the nanoparticles more specifically to cancer cells. We have tried three methods of incorporation of Chitosan in the nanoparticles, but only one was efficient. The first ...
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