Drug Delivery Applications Articles & Analysis
46 articles found
Induced pluripotent stem cells (iPSCs) have revolutionized the field of regenerative medicine and cellular biology. They are derived from somatic cells that have been genetically reprogrammed back into an embryonic-like pluripotent state. This transformation enables them to differentiate into any cell type, offering significant potential for disease modeling, drug discovery, and therapeutic ...
Chemical synthesis is particularly beneficial for generating complex and modified lipids that may not be easily isolated from natural sources. One notable application of chemical synthesis is in the development of lipid conjugates used in drug delivery systems. ...
Researchers must control these variables to ensure accurate and reproducible results. Applications in Drug Development The MDCK permeability assay plays a vital role in the screening of new drug candidates. ...
Watertown, MA – March 24, 2025 – Biopharma PEG, a leading supplier of high-quality polyethylene glycol (PEG) derivatives, highlights its innovative product DSPE-PEG-Mannose, an advanced biomedical polymer with significant potential in drug delivery, tumor-targeted therapy, tissue recognition, and adhesion.Structural Advantages of DSPE-PEG-MannoseDSPE-PEG-Mannose ...
In the rapidly evolving field of cellular biology and genetic engineering, the development of efficient and reliable cell lines is vital for research and therapeutic applications. One such advancement is the establishment of the Monkey DLL3 stable cell line using HEK293T cells. This article provides an overview of the significance of this cell line, its applications, and the methodology behind ...
They are FDA-approved and often used in various applications, from sutures to drug delivery systems. Similarly, PEG copolymers also boast high biocompatibility, as they are associated with a minimal immunogenic response. ...
Compounds of phosphorus play a pivotal role in various fields, notably pharmaceuticals and industrial chemistry. Their unique chemical properties, such as reactivity and ability to form diverse structures, make them invaluable in drug synthesis and other industrial applications. This article delves into the chemical characteristics of phosphorus compounds, their applications in drug development, ...
The Importance of ADME Testing The intricate journey of a drug begins once it is administered to a patient. Understanding how a substance behaves within biological systems can significantly impact the formulation and delivery methods chosen by researchers. ...
Pharmaceutical Development: These cell lines are essential in the drug discovery pipeline, allowing for high-throughput screening and functional assays to evaluate drug efficacy and safety. Biotechnology Applications: Beyond disease research, knockin technologies are employed to create cell lines producing therapeutic proteins, monoclonal ...
Alfa Cytology has introduced its advanced drug development services for brain tumors. Alfa Cytology, celebrated for its cutting-edge biotech solutions and extensive tumor research expertise, has recently introduced brain tumor drug development services, designed to empower researchers in understanding the intricacies and unique challenges associated with brain ...
Antibody drugs are a type of drugs that treat diseases through artificially synthesized antibodies, which bind specifically to target molecules for therapeutic purposes. Common types of antibody drugs include monoclonal antibodies, artificially synthesized antibody fragments, immunotoxins, and antibody-drug conjugates, etc. Antibody drugs have shown significant therapeutic effects in the ...
Glycosylation impurities are a type of chemical commonly encountered in biochemical, medical, and pharmaceutical chemistry research. The presence of these impurities can affect the efficacy, safety, and stability of drugs. Therefore, the detection and analysis of glycosylation impurities are crucial in ensuring the quality and therapeutic effectiveness of pharmaceutical products.What are ...
Antibodies are an essential part of our immune system, capable of recognizing foreign molecules (antigens) and helping to eliminate them. Antibodies have a high degree of target specificity, affinity, and safety, and have been widely used in the treatment, diagnosis, and prevention of many major diseases. They are currently a focus in new drug development. The design of antibody drugs is a ...
Circular Dichroism (CD) uses the absorption properties of optically active substances to analyze the molecular structure of drugs. It has very valuable applications in drug analysis, including:1. ...
Antibody drugs, particularly monoclonal antibodies (mAb), play a critical role in the treatment of many diseases, especially in the treatment of cancer and immunological disorders. To ensure the effectiveness and safety of these antibody drugs, it is necessary to perform activity testing.Definition of Antibody ActivityThe activity of an antibody drug usually refers to its ability to bind to the ...
They also have a high degree of stability and solubility, making them suitable for various routes of administration. One of the first applications of nanobodies in drug delivery was the development of targeted drug delivery systems. ...
Introduction Cellular mechanisms driving cell death play a crucial role in various physiological and pathological processes. One such mechanism is apoptosis, a tightly regulated process vital for maintaining tissue homeostasis, development, and immune response. Apoptosis assays are valuable tools used by researchers to study the intricate details of this cellular event. This blog aims to ...
For example, through carboxylic acid functional groups, PEGs can covalently bind to drugs, targeting ligands, or other biologically active molecules, thus enabling drug-targeted delivery and controlled release. In addition, carboxylic acid PEGs can be involved in regulating interactions with cells, such as fusion with cell membranes and cellular ...
Microneedles have gained significant attention in recent years for their potential in drug delivery applications. These tiny needles, typically measuring less than 1 mm in length, can painlessly penetrate the skin and deliver drugs in a precise and controlled manner. ...
In this article, we will explore different types of nanoparticle development that are revolutionizing drug delivery systems. Polymer Nanoparticles for Drug Delivery Polymer nanoparticles are a popular choice for drug delivery systems due to their biocompatibility and versatility. ...