Drug Design And Development Articles & Analysis: Older
262 articles found
Recombinant protein drugs refer to protein products that originate from animals and plants and are developed through biotechnology research. ...
Understanding this relationship helps in dosing regimen optimization, ensuring that therapeutic levels are achieved without crossing into toxicity. Integrating PK and PD for Drug Development Integrating PK and PD in drug development is a powerful approach to optimize therapeutic strategies. By modeling and simulating these ...
The world of drug development has long been marked by the rigorous assessment of cardiac safety. ...
Understanding the complex world of drug discovery and development necessitates familiarity with key players in cellular communication. ...
In response to these challenges, Alfa Cytology’s therapeutic antibody development services are meticulously designed to cater to the unique molecular characteristics of bladder cancer. ...
These technologies allow researchers to predict viral behavior, identify potential targets, and expedite the drug development process. For example, companies are exploring the use of broad-spectrum antivirals that can inhibit multiple strains of viruses, providing a safeguard against emerging viral threats. ...
In vitro permeability assay kits play a crucial role in the field of pharmaceutical development, particularly when evaluating the absorption characteristics of drugs. These kits allow scientists and researchers to investigate how compounds permeate biological membranes, which is vital for understanding drug bioavailability. Understanding Permeability Permeability refers to the ability of a ...
HCEC-12 is a well-established human corneal epithelial cell line derived from human corneal tissue. It plays a crucial role in ocular research, particularly for studies related to corneal physiology, wound healing, and the pathogenesis of various ocular diseases. This article delves into the characteristics, applications, and significance of the HCEC-12 cell line in biological and medical ...
Solid-Phase Peptide Synthesis (SPPS) Developed by Robert Bruce Merrifield in the 1960s, SPPS revolutionized peptide synthesis. ...
Remember those mRNA vaccines? They were developed at unprecedented speed, thanks to the work of enzymes that enabled the rapid and large-scale production of mRNA. ...
Alfa Cytology has introduced its advanced drug development services for brain tumors. Alfa Cytology, celebrated for its cutting-edge biotech solutions and extensive tumor research expertise, has recently introduced brain tumor drug development services, designed to empower researchers in understanding the ...
Peptide drugs are bioactive protein fragments composed of short chains of amino acids. Due to their high efficiency, specificity, and relatively low toxicity and immunogenicity, they occupy an important position in modern medicine and drug development. They have shown great potential in treating various diseases, such as cancer, autoimmune diseases, infectious diseases, and metabolic disorders. ...
Within the rapidly advancing realm of biotechnology, zebrafish genome editing services are carving a niche, heralding a new epoch in genomics and cellular research. This development is driving innovative research approaches, empowering researchers to create effective models to comprehend complex genetic interactions and responses quickly and efficiently. Zebrafish, also known as Danio rerio, ...
GMP growth factors and cytokines designed for therapeutic manufacturing are an essential component of defined media. ...
Progress in Liposomal Drug Delivery Over the past few decades, liposome technology has advanced significantly, with several liposome-based formulations approved for clinical use and many more in various stages of development. ...
Clinical trials are the backbone of modern medicine, responsible for bringing innovative, safe, and efficient treatments to market after rigorous testing and evaluation. However, the conventional process of conducting these trials has often been long, expensive, and fraught with inefficiencies¹. The advent of predictive analytics is reshaping the landscape of clinical trials, ushering in a ...
Collagen is a crucial structural protein, widely presenting in human skin, bones, tendons, ligaments, and other tissues. It's essential for maintaining the structural integrity and function of tissues. The measurement of collagen can help researchers and physicians understand the pathological process of related diseases (such as osteoporosis, arthritis, skin aging etc.), and also aid in drug ...
Therefore, the detection of sialic acid proteins holds significant value in disease diagnosis, biomedical research and drug development.Biological Importance of Sialic Acid ProteinsSialic acid proteins play an indispensable role in many physiological and pathological processes. Under normal conditions, they participate in intercellular communication, regulation of immune ...
Medical advancement relies on clinical trials, which are essential for the development of safe and effective innovative treatments. However, the success and general applicability of these treatments heavily depend on the diversity of the participants involved¹?³. This blog explores the importance of achieving data diversity in clinical trials to enhance clinical trial results and ...
Peptidomimetic development involves the design and synthesis of molecules that mimic three-dimensional structures and functional groups of natural peptides. ...