Refine by
Drug Discovery Process Articles & Analysis: Older
18 articles found
Understanding the complex world of drug discovery and development necessitates familiarity with key players in cellular communication. ...
Glycan-Based Drug Discovery The study of glycan structures has led to the discovery of novel drug candidates targeting glycan-related pathways. ...
Due to all the previously described advantages presented by the zebrafish animal model, it has recently come to the fore in the drug discovery process (i) to identify molecules that specifically ameliorate disease phenotypes and (ii) to conduct detailed characterization studies around optimizing compounds with a focus not only on efficacy ( ...
By leveraging machine learning algorithms and computational tools, researchers can accurately predict the impact of genetic modifications and optimize the editing process. This not only accelerates the pace of research but also enhances the efficiency and accuracy of gene editing techniques, such as CRISPR-Cas9. ...
By leveraging machine learning algorithms and computational tools, researchers can accurately predict the impact of genetic modifications and optimize the editing process. This not only accelerates the pace of research but also enhances the efficiency and accuracy of gene editing techniques, such as CRISPR-Cas9. ...
The process of drug discovery is a complex and multifaceted endeavor, involving the integration of diverse scientific disciplines, including biology, chemistry, and computational science. ...
One critical element in the drug development process is drug metabolism and pharmacokinetics (DMPK), which refers to how a drug is absorbed, distributed, metabolized, and excreted (ADME) from the body. ...
One critical element in the drug development process is drug metabolism and pharmacokinetics (DMPK), which refers to how a drug is absorbed, distributed, metabolized, and excreted (ADME) from the body. ...
This article explores the various approaches, software tools, and techniques employed in molecular docking and highlights their potential in accelerating drug discovery. The Importance of Molecular Docking: Small molecules bind to proteins within surface cavities, making it essential to predict and understand these interactions accurately. ...
In the dynamic realm of drug discovery, the pursuit of innovative and effective treatments for diverse diseases demands groundbreaking approaches that can expedite the drug development lifecycle. ...
In the realm of modern medicine, the quest for new and effective drugs to combat various diseases is a continuous journey. Drug discovery, the process of identifying compounds that can potentially treat diseases, has seen a significant transformation in recent years, thanks to advancements in computational biology and artificial ...
Moreover, immortalized cell lines play a crucial role in drug discovery and development. They provide a cost-effective and efficient platform for testing the efficacy and toxicity of potential therapeutic agents. ...
In the fast-paced realm of drug discovery, scientists constantly seek innovative approaches to efficiently and cost-effectively identify potential drug candidates. ...
We heard from leaders who are applying AI at various stages across the drug discovery and development process. While the approaches differ, the overarching goal is often the same: bring better medicines to patients with less failure. ...
The pharmaceutical industry has a notoriously slow business model, where a typical drug discovery program can take many years to successfully progress to a ready-to-prescribe drug. ...
The function of sphingolipids Sphingolipids are essential structural components of cell membranes. Further discoveries have revealed the association of sphingolipids with signaling pathways related to the regulation of cell growth, differentiation, and death. Sphingolipids play important roles in various life processes, including tumor evolution, the development ...
The information content in the maps, which include contributions from protein flexibility and both protein and functional group desolvation contributions, can be used in many aspects of the drug discovery process. These include identification of novel ligand binding pockets, including allosteric sites, pharmacophore modeling, prediction of ...
I wanted to learn and grow in that space, and always hoped to work at a place where my contributions could impact a greater cause. Recursion’s interview process gave me a lot of insight into the company values and culture; which I found to be highly collaborative, interdisciplinary ("One Recursion"), and a place where growth mindset ("We Learn") goes a long way. Recursion ...