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Drug Discovery Process Articles & Analysis: This-Year

6 articles found

Kinase Screening Services: Unlocking the Path to Targeted Therapeutics

Kinase Screening Services: Unlocking the Path to Targeted Therapeutics

In the realm of drug discovery, kinase screening services have emerged as a pivotal tool for understanding complex cellular signaling pathways and identifying potential therapeutic targets. ...

ByCreative Bioarray


Human tumor response to novel natural product compounds using the POAI biobank and active machine learning

Human tumor response to novel natural product compounds using the POAI biobank and active machine learning

Through this project, the POAI active machine learning technology constructed a predictive model of tumor sample response to NPDC’s targeted drugs in a highly efficient manner, saving approximately 18 months of wet lab work in the process. ...

ByPredictive Oncology Inc.


Understanding Caco-2 Permeability Assay: A Critical Tool for Drug Development

Understanding Caco-2 Permeability Assay: A Critical Tool for Drug Development

In the realm of pharmacology and drug development, the assessment of drug permeability is essential. One of the most widely recognized in vitro models for evaluating the intestinal absorption of compounds is the Caco-2 permeability assay. ...

ByCreative Bioarray


Unlocking Drug Potential with Spray Drying: A Must-Have Tool for R&D

Unlocking Drug Potential with Spray Drying: A Must-Have Tool for R&D

In our last blog, Peter discussed how AI is accelerating the drug discovery process and putting pressure on chemists, who must find ways of developing these potential drugs for subsequent testing or production. ...

ByBUCHI


S9 Metabolic Stability: A Key to Drug Development

S9 Metabolic Stability: A Key to Drug Development

This preparation contains a mixture of metabolic enzymes, including cytochrome P450s, which play a pivotal role in drug metabolism. By utilizing the S9 fraction in assays, researchers can simulate the metabolic processes that a drug will encounter in a living organism. ...

ByCreative Bioarray


Comprehensive Disease Models for Preclinical Drug Discovery

Comprehensive Disease Models for Preclinical Drug Discovery

Preclinical drug discovery represents a critical phase in the development of new therapeutics. ...

ByCreative Biogene

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