drug release control Articles
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Characterisation and controlled drug release from a novel two-phase hydrogel system
In this work, a two-phase hydrogel system was prepared by physically imbedding a xerogel in the core of a cryogel which was freeze thawed. The cryogels were prepared with poly (vinyl alcohol) (PVA) and poly (acrylic acid) (PAA) while the xerogels were prepared by UV polymerisation of 1-vinyl-2-pyrrolidinone (NVP), acrylic acid (AA) and various percentages of ibuprofen sodium salt. Mechanical and ...
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Classification of Excipients for Transdermal Drug Delivery System
Transdermal drug delivery system is a type of drug formulation that is absorbed into the body circulation through capillaries at a certain rate through the skin to produce drug effects. Transdermal drug delivery systems allow the drug to continuously diffuse through the skin, penetrate and absorb into the blood circulation, maintain stable blood concentrations for a long time, reduce the ...
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Eight Excipients for Transdermal Drug Delivery Systems Materials
Transdermal drug delivery systems have gained considerable importance in the pharmaceutical industry due to their convenience, effectiveness, and ease of use. These systems rely on various excipients, which are inactive substances that aid in the delivery and absorption of active drug compounds through the skin. In this article, we will discuss eight important excipients commonly used in ...
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Nanoparticle Development: Revolutionizing Drug Delivery Systems
The field of medicine is constantly evolving, with researchers and scientists striving to find innovative ways to deliver drugs effectively and efficiently. One of the most promising technologies that has emerged in recent years is nanoparticle development for drug delivery systems. Nanoparticles are tiny particles with dimensions in the nanometer range, making them ideal for targeting specific ...
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How to Prepare Drug Microcapsules: A Holistic Approach
Microencapsulation technology has revolutionized drug delivery systems, allowing for the protection and controlled release of therapeutic agents. Microcapsules, tiny spherical structures capable of encapsulating drugs, offer numerous advantages in terms of stability, targeted delivery, and improved patient outcomes. In this article, we will delve into the methods involved in preparing drug ...
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Applications of the High Polymers in Medical Science
Introduction With the wide application of high polymers, more and more extensive researches on high polymers have been conducted in recent years. Many papers and monographs discussed the important characteristics of high polymers and their important applications in medicine. Macromolecule/high polymers can be used in surgery, suture, orthopedic fixation and tissue repair. They can also be used as ...
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Types and Application Value of Enzyme Engineering
As a biocatalyst, enzyme has been widely used in various production fields of light industry. In recent decades, with the continuous technological breakthroughs in enzyme engineering, it has become more and more widely used in industry, agriculture, medicine and health, energy development and environmental engineering. Food processing applications The biggest use of enzymes in the food ...
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The Development History and Applications of Enzyme Engineering
Enzyme engineering is a scientific technology that puts enzymes or microbial cells, animal and plant cells, organelles, etc. in a certain biological reaction device, and then use the biocatalytic function of the enzyme to transform the corresponding raw materials into useful substances and apply them to social life with the help of engineering means. It includes the preparation of enzyme ...
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The Limitations and Challenges of Cancer Therapies
Considerable investment into cancer research has led to the development of remarkable new therapies, which have greatly improved therapeutic outcome for the countless individuals diagnosed with cancer. Until recently, almost all therapies that were granted clinical approval were small molecules. However, biotechnological advances in the last several decades have made it possible to develop ...
By Indee Labs
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Biopharma PEG Provides Multi-arm PEG Derivatives Crosslinked Into Hydrogels
Polyethylene (ethylene glycol) is a hydrophilic polymer that can have a very high water content when cross-linked into a network. Polyethylene glycol (PEG) is a suitable material for biological applications because it does not normally elicit an immune response. Since the 1970s, PEG has been used to modify therapeutic proteins and peptides in order to increase their solubility, reduce their ...
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What makes Biodegradable Microspheres ideal for Controlled-release Drug Delivery?
Patient-centric drug development is a divisive concept. Dismissed as a buzzword by some. Adopted extensively by others. It has, nevertheless, gained enormous traction over the last decade. This new approach to treatment incorporates patient perspectives into drug development. A key benefit is the keener focus on convenience and safe drug administration. Traditional approaches, prioritising ...
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Microneedle Patch Technologies: Innovations in Drug Delivery
Microneedle patch technologies have revolutionized the field of drug delivery, offering a wide range of advantages over traditional methods. These innovative patches provide a minimally invasive and painless alternative to injections while ensuring precise and controlled drug administration. In this article, we will explore various types of microneedle patch technologies, including ...
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What Are the Methods for Preparing Microspheres?
Microspheres play a crucial role in the field of pharmaceuticals, biotechnology, and materials science due to their unique properties and applications. These spherical particles, ranging from a few micrometers to several millimeters in size, have a wide range of uses, including drug delivery systems, cell encapsulation, and as supports for various chemical reactions. Polymeric microspheres, ...
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Biopharma PEG’s Azide PEG Series for Pharmaceuticals
Biopharma PEG, a leading innovator in polyethylene glycol (PEG) derivatives, proudly introduces its featured Azide PEG series, which can be used in drug development, click chemistry, ADCs (Antibody Drug Conjugates), PROTACs (Proteolysis Targeting Chimeras), and beyond. This Azide PEG features monodispersed PEGs such as N3-PEG4-OH, N3-PEG3-COOH, N3-PEG11-NH2, N3-PEG3-NHS ester, ...
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Micelle vs Liposome
Micelles refer to molecularly ordered aggregates that begin to form in large quantities after the surfactant concentration reaches a certain value in an aqueous solution. In micelles, the hydrophobic groups of surfactant molecules aggregate to form the core of the micelle, and the hydrophilic polar groups form the outer layer of the micelle. Liposomes are an artificial membrane. In the water, the ...
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Four Novel Drug Delivery Systems You Should Know
In the field of medicine, effectively delivering drugs to the target site in the body is crucial for successful treatment. Over the years, several innovative drug delivery systems have been developed to improve drug efficacy and patient outcomes. In this article, we will discuss four novel drug delivery systems that have shown promising results in recent research. These systems include ...
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Exploring the Potential Applications of Fluorescent Microspheres
Microspheres are small spherical entities formed by dispersing or adsorbing drugs in a polymer matrix. The particle size is typically between 1 μm and 250 μm, and the largest can reach more than 800 μm. Microsphere technology is at the intersection of cutting-edge disciplines such as materials science, polymer technology, medical technology, and microelectronics. Once injected into the ...
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New Method to Produce Ring-Opening Metathesis Polymers with Facile Degradability
A team of chemists at MIT has formulated a method to produce polymers that can disintegrate more readily in the body as well as in the environment. A new type of polymer designed by MIT chemists incorporates a special monomer (yellow) that helps the polymers to break down more easily under certain conditions. (Image credit: Demin Liu) A chemical reaction known as ring-opening metathesis ...
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