Enrolls First Patients Articles & Analysis
24 articles found
Empagliflozin in HFpEF (EMPEROR-Preserved) The EMPEROR-Preserved trial, released in 2021, is the first randomized controlled trial testing the efficacy and safety of SGLT2is (empagliflozin) in patients with HFpEF. The therapy was able to significantly reduce cardiovascular death or hospitalization in patients with HFpEF. [3] The randomized, ...
DSTP3086S, a humanized IgG1 anti-steap1 monoclonal antibody related to MMAE, demonstrated safety and significant antitumor activity in a Phase I trial of 77 mCRPC patients. PSA decreased by 50% in 18% of patients, local radiation reaction occurred in 6% of patients, and transformation to benign cycle tumor cells <5 in 60% of ...
With the rising demand for improving patient safety in clinical trials, the adoption of patient-centric solutions is considered the best route to enhance data accuracy and experience automated workflows. This is where eCOA comes into play. In this blog post, we will find out how electronic clinical outcome assessments are helping the clinical trials industry handle the ever-growing list of ...
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The SIAP study investigates the effect of using Ergotrics' Inflatable Prone Support (IPS) on intra-abdominal pressure (IAP) during spine surgery. Study background The objective of this study is to demonstrate the ability of the inflatable Prone Supports (IPS) to lower the IAP of patients in the prone position. Whenever the patients’ position is changed to prone, the IAP is increased due to ...
Reckamp will present the trial results at the ASCO meeting. "This is the first trial to show a survival benefit of ICI and VEGFR inhibition in patients with advanced lung cancer who have experienced tumor progression in a previous ICI," Reckamp said. ...
For the first time, heart failure patients can have full visibility of their hearts’ LA pressure and self-adjust their medication to stop further deterioration and avoid hospitalizations April 26, 2022 08:30 AM Eastern Daylight Time TEL AVIV, Israel–(BUSINESS WIRE)–Vectorious Medical Technologies Ltd., today announced that it has ...
ABILITY Diabetes Global (Randomized Comparison of Abluminus DES+ Sirolimus-Eluting Stents versus Everolimus-Eluting Stents in Coronary Artery Disease Patients with Diabetes Mellitus Global) started off with the index patient enrolment on 11th June 2020 in Italy (at the peak of the 1st wave of COVID-19 pandemic) by P.I. Prof. Antonio Colombo and the pace of enrolment since then has been steady and ...
In the developed world, 1 in 4 people die from cancer or cancer-related disease, and cancer accounts for 13% of deaths globally. Oncology is the fastest growing therapeutic area by revenue and number of clinical trials. There’s been a huge emphasis on developing new treatments to improve survival in patients with cancer, but these trials have become a costly undertaking for sponsor ...
This pivotal study (NCT04960202) enrolled 2,246 patients with COVID-19, 1,120 received Paxlovid and 1,126 received placebo. ...
Abstract Background Impaired neuromuscular control and degeneration of the multifidus muscle have been linked to the development of refractory chronic low back pain (CLBP). An implantable restorative-neurostimulator system can override the underlying multifidus inhibition by eliciting episodic, isolated contractions. The ReActiv8-B randomized, active-sham-controlled trial provided ...
Prospective, multicenter, randomized, crossover study. Chronic corneal edema patients were randomized to one of two arms. The first arm was fitted with the Therapeutic Hyper-CL™ lens while the second arm was fitted with a standard soft bandage contact lens. ...
Abstract Almost all patients achieved sustained virological response (SVR) by direct-acting antivirals (DAA) therapy, but it is not clear as to what extent DAA therapy affects changes in liver fibrosis after achieving SVR. In this study, we investigated the changes of liver stiffness by magnetic resonance elastogaraphy (MRE) during DAA therapy. A total of 308 patients were enrolled in the study. ...
In real time, a physician can remotely adjust the patient’s medication based on the data. The device is the subject of the VECTOR-HF study, which is designed to enroll 45 patients with chronic New York Heart Association heart failure class III, hospitalization for worsening heart failure, or elevated ambulatory B-type natriuretic peptide ...
” As summarized in Circulation: Cardiovascular Interventions, this prospective, multicenter, single-arm study enrolled patients with symptomatic PE and RV/LV diameter ratio ≥ 0.9 as documented by computer tomography angiography. ...
” MOTION is designed to enroll 30 patients between Cleveland Clinic and a second study site, UNC Medical Center in Chapel Hill, North Carolina. ...
In addition, up to one third of these patients are readmitted to the hospital within the first ten years post treatment. ...
Where is the technology in development and what is next for the company? We began enrolling patients in our ACTIVATE I first-in-human trial in May of 2020. The phase I study is evaluating the safety and efficacy of the AlucentNVS technology in patients with PAD of the lower extremities. The first ...
Quick Facts LOCATION: San Diego, CA MARKET SECTOR: Hospital FACILITY SIZE: 1,030,000 square feet FACILITY PEAK LOAD: 6.8 MW EQUIPMENT: 4.6 MW Solar Turbines Mercury™ 50 gas turbine, absorption chiller FUEL: Natural Gas USE OF THERMAL ENERGY: Space and autoclave heating, absorption chilling and domestic hot water CHP TOTAL EFFICIENCY: 64% ENVIRONMENTAL BENEFITS: Less than 5ppm NOx TOTAL ...
The company just completed enrollment of the FMR cohort. The company expects to file in the first quarter of next year for its pivotal study. Ancora also has a pivotal study for a CE mark, with it seeing the first few patients enrolled. “What’s exciting for us is the enrollment ...
These are certainly important first steps, as are some regional attempts at curbing the opioid epidemic. ...