Fibrosis Marker Articles & Analysis
3 articles found
Idiopathic pulmonary fibrosis (IPF) is a devasting lung disease characterized by progressive scarring of lung tissue. As fibrosis develops, patients experience worsening shortness of breath, reduced lung capacity and ultimately respiratory failure. Current therapies for IPF rely on oral administration of pirfenidone and nintedanib, two FDA-approved drugs that slow disease progression. While ...
Alterations in serum N-glycan profiles now serve as early detection biomarkers for liver fibrosis, outperforming traditional markers. Meanwhile, aberrant O-glycosylation in mucins creates the CA125 epitope used to monitor ovarian cancer progression. ...
In bacterial taxa-metabolites networks according to fibrosis severity, strong inverse interactions betweenVeillonellaceaeandRuminococcaceaeare noticeable and observed only in non-obese NAFLD subjects, implying the potential of the microbiome-based marker to diagnose fibrosis in non-obese NAFLD. ...