gene regulatory network Articles
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Exposure to a PBDE/OH‐BDE mixture alters juvenile zebrafish (Danio rerio) development
Polybrominated diphenyl ethers (PBDEs) and their metabolites (e.g. hydroxylated BDEs (OH‐BDEs)) are contaminants detected together frequently in human tissues, and are structurally similar to thyroid hormones (TH). THs partially mediate metamorphic transitions between life stages in zebrafish, making this a critical developmental window which may be vulnerable to chemicals disrupting thyroid ...
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CD Genomics Perspective: Using RNA Sequencing Technology to Study Ecology
The massive growth of transcriptomics beyond clinical biology and into the fields of ecology and evolution has been fueled by RNA sequencing (RNA-seq). RNA-seq promised unprecedented sensitivity for sensing the expression differences among rare transcripts, splice variants, and microRNAs, then quickly surpassing microarrays as the high-throughput method for studying differential expression in ...
By CD Genomics
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Protein PPARd Can Induce Rapid Maturation of Human Pluripotent Stem Cell-Derived Cardiomyocytes
In a new study, researchers from the Icahn School of Medicine at Mount Sinai have developed a reproducible and scalable method to advance the maturation of human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs), and hPSC-CMs produced by human stem cell lines in the laboratory support myocardial contraction, which will improve methods for disease modeling, regenerative therapy, and drug ...
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The Small RNA Sequencing Service Is Now Available Through RNA Solutions Platform
RNA Solutions is a platform that offers services for the revolutionizing study of RNA, targeting both coding and non-coding RNAs of different physiological functions. The scientists at CD Genomics are ready to help detect various types of RNA via meticulous and integrative approaches. Recently, the company announced Small RNA Sequencing, which helps researchers quickly identify known and unknown ...
By CD Genomics
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A Comprehensive Guide to CRISPR Screening and Sequencing: Methods, Applications, and Challenges
In competition with bacteriophages, bacteria and archaea have evolved unique ways of defending, which include the CRISPR/Cas systems and the immune systems of bacteria and archaea, which resist the invasion of foreign DNA or RNA and recognize the foreign invaders and cleave them for immune defense. CRISPR/Cas systems are now useful research tools that are easy to use and work well in the field of ...
By CD Genomics
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