Refine by
Genetic Material Articles & Analysis
39 articles found
These nanoparticles mimic the structure of viruses but lack the viral genetic material that makes viruses infectious. This unique characteristic offers a versatile platform for various innovative applications without the associated risks of viral infections. ...
Moreover, the availability of these immortalized cells allows for greater exploration of genetic and molecular mechanisms underlying podocyte function. Researchers can manipulate the genetic material of these cells to study the effects of specific genes or pathways involved in podocyte physiology and pathology. ...
In recent years, the field of gene editing has experienced groundbreaking advancements, with CRISPR/Cas9 emerging as a powerful technology for precise genetic manipulation. Among various delivery systems, lentiviruses have garnered significant attention due to their ability to introduce genetic material into both dividing and non-dividing cells, ...
Adenoviruses are a group of viruses that have gained significant attention in recent years, particularly in the fields of gene therapy, vaccine development, and cancer treatment. With their ability to deliver genetic material into cells effectively, adenoviruses serve as valuable vectors in various biomedical applications. ...
Understanding Recombinant Vaccines Recombinant vaccines are created by inserting genetic material from a pathogen into a host cell. This host cell, often a yeast or bacteria, then produces antigens that mimic the pathogen’s characteristics. ...
In the rapidly evolving field of cellular biology and genetic engineering, the development of efficient and reliable cell lines is vital for research and therapeutic applications. ...
S Phase (Synthesis Phase) l DNA replication occurs, ensuring that genetic material is duplicated for the next generation of cells. l Any errors in DNA copying can lead to mutations, making this phase a critical checkpoint. 3. ...
These metabolites offer critical clues into disease processes that cannot be captured through traditional genetic or protein-based analyses. In cancer, for example, exosomes often carry altered metabolite profiles, including changes in amino acid metabolism and nucleotide biosynthesis, which reflect the high-energy demands of rapidly proliferating tumor cells. ...
Knockin cell line generation represents a pivotal advancement in genetic engineering, providing vital tools for biological research and therapeutic development. ...
Researchers often select for stable cell lines by integrating antibiotic resistance genes alongside target genes, enabling them to isolate and cultivate only those cells that incorporate the desired genetic material. In the realm of biotechnology and pharmaceuticals, stable cell lines serve as a foundation for producing high-yield protein therapeutics, monoclonal ...
These probes are specifically designed to target and bind to the genetic material within CAR-T cells, enabling researchers to accurately track and monitor their presence in biological samples. ...
The Vaccines can be formulated using various platforms, including: ·Peptide/Protein Vaccines: Short sequences of the target antigen are synthesized and administered to patients. ·DNA/RNA Vaccines: Genetic material encoding the target antigen is delivered to patient cells, enabling the production of the antigen within the body. ...
Introduction For years, scientists have leveraged the brilliant potentialities of genetic science to explore how cells function and interact in living organisms. ...
Transforming a pathogen into a potential cure requires a meticulous understanding of viral morphology, functionality, and manipulation principles that govern the genetic framework. Oncolytic Viruses are wrought using an array of techniques, each technique contingent on the virus strain and the cancer form it targets. ...
Epigenetic regulation involves a gamut of sophisticated and precisely regulated processes that control the machinery responsible for transcribing genetic material from DNA to RNA. These mechanisms manipulate gene expression through alterations in the epigenetic landscape, which include DNA methylation, histone modification, chromatin remodeling, and non-coding ...
Chimeric RNA refers to a type of RNA molecule that is formed by the fusion of genetic material from two or more distinct genes. These chimeras can arise through different mechanisms, including chromosomal translocation, cis-splicing, or trans-splicing. ...
They act as molecular scribes, meticulously transcribing the genetic information from DNA templates into mRNA. This transcriptional machinery ensures the accurate and efficient generation of mRNA, a critical component of mRNA vaccines. ...
It allows comprehensive, high-resolution analysis of genetic material, which is a prerequisite for addressing various health, research and industry-related questions. LAM-PCR, a modification of conventional PCR, offers significant advancements over traditional methods, providing a comprehensive, unique and practical approach to genetic analysis. ...
Eukaryotic cells, as mentioned, possess a distinct nucleus containing deoxyribonucleic acid (DNA) as the major component. This nucleus holds the genetic material of the organism. During active cell division, this genetic material organizes into chromosomes, while chromatin refers to its structure during the developmental phase. ...
Bacteria are a diverse group of organisms in terms of physical features such as size and shape, physiological attributes, and genetic make-up. Bacterial species such as E. coli, Pseudomonas, Salmonella, etc., are commonly used as model organisms in the study of microbiological concepts in physiology, health, food, and ecology. ...