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Genome Sequence And Structural Articles & Analysis: Older

9 articles found

Karyotype Analysis for Rare Disease

Karyotype Analysis for Rare Disease

Many rare diseases have obvious manifestations of chromosomal structural abnormalities, making it a strategy to determine the cause of diseases from a macroscopic perspective of genetics. ...

ByProtheragen


Pan-Genome Analysis: Overview, Workflow, Application and Recent Advances

Pan-Genome Analysis: Overview, Workflow, Application and Recent Advances

Pan-genomes reflect structural variation (SV) and polymorphisms in the genome, allowing in-depth comparisons of variation at the species level or at higher taxonomic levels. ...

ByCD Genomics


Study on Partial Glycoprotein of Feline Herpesvirus Type 1

Study on Partial Glycoprotein of Feline Herpesvirus Type 1

In addition to often invading the respiratory system, it can also infringe on the reproductive system, nervous system, conjunctiva and embryos. FHV-1 Genome Structure and Encoded Glycoproteins FHV-1 is a double-stranded DNA virus with an envelope. The full genome sequence is 126-134 kbp, and the GC content in the base is about ...

ByCreative Diagnostics


Applications of Microbial Whole Genome Sequencing

Applications of Microbial Whole Genome Sequencing

They are generally divided into fungi, actinomycetes, bacteria, spirulina, rickettsia, chlamydia, mycoplasma and viruses. Microbial whole genome sequencing is an important tool for mapping genomes of novel organisms, finishing genomes of known organisms, or comparing genomes across multiple samples. ...

ByCD Genomics


Long Read Sequencing Fills in the Missing Pieces of Genomics

Long Read Sequencing Fills in the Missing Pieces of Genomics

Long read sequencing has great application in the direction of de novo genome sequencing and resequencing, especially to improve the accuracy of detecting repeat regions, structural variants, as well as complex regions. Researchers used long read sequencing to produce haploid human genome ...

ByCD Genomics


Back to blog Federated Architecture in Genomics

Back to blog Federated Architecture in Genomics

Pharmaceutical companies recognize the growing value of genome data, partnering with biobanks to power massive sequencing projects such as AstraZeneca’s 2 Million Genomes Project and Boehringer Ingelheim joining a nation-wide research collaboration in Finland to analyse 500K genomes. ...

ByLifebit


Introduction to AAV as a Gene Therapy Vector, Part 1

Introduction to AAV as a Gene Therapy Vector, Part 1

Second, cellular machinery translates AAV’s viral genome into proteins which assemble into a viable viral shell with a copy of the viral genome packaged inside it. ...

ByDyno Therapeutics


Complexity metrics for ontology based information

Complexity metrics for ontology based information

An ontology defines technical terms and shows interrelationships between terms for particular application areas. XML-based standards such as OWL and DAML provide mechanisms to produce XML based ontologies. Ontologies are used in service matching and dynamic web service composition, and are heavily used in bioinformatics and genomics to characterise the structure of living things. Our research ...

ByInderscience Publishers


Morphology, genome sequence, and structural proteome of type phage p335 from lactococcus lactis

Morphology, genome sequence, and structural proteome of type phage p335 from lactococcus lactis

Morphologically, P335 resembled the L. lactis phages TP901-1 and Tuc2009, except for a shorter tail and a different collar/whisker structure. Its 33,613-bp double-stranded DNA genome had 50 open reading frames. Putative functions were assigned to 29 of them. Unlike other sequenced genomes from lactococcal phages belonging to this ...

ByAmerican Society for Microbiology (ASM)

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