Gut Microbiome Articles & Analysis: Older
23 articles found
In addition to their role in fat and cholesterol metabolism, bile acids possess antimicrobial properties, which can help to maintain a balanced gut microbiome and prevent the overgrowth of harmful bacteria. This antimicrobial function is particularly relevant in the context of digestive health, as an imbalance in gut microbial populations has ...
Furthermore, targeted therapies designed to modulate bile acid synthesis have shown promise in ameliorating BAD symptoms, offering hope for improved patient outcomes. The Gut Microbiota Influence Emerging research has unraveled the intricate interaction between bile acids and the gut microbiota. The gut microbiome has been ...
Probiotics have gained popularity in recent years, as more people have become aware of the crucial role of the gut microbiome in maintaining overall health. The gut microbiome consists of trillions of microorganisms, including bacteria, viruses, and fungi, that reside in the gastrointestinal tract. ...
However, many strains are a normal part of the human microbiome. E. coli are one of the first bacteria to colonize an infant’s gut at birth, but by age one they are reduced to a minor player in the microbiome. ...
Drugs may affect host metabolism or clinical efficacy by positively and negatively modulating the gut microbiome. Not only antibiotics medicines, but also other commonly used drugs have been shown to affect the gut microbiome in population-based studies. Approaches to the Gut Microbiome There ...
Recently, a research paper published in Nat Commun entitled "Gut microbiome of the largest living rodent harbors unprecedented enzymatic systems to degrade plant polysaccharides" specifically studied the enzymatic strategies and metabolic pathways used by dolphins to decompose their microbial symbiotic communities of dietary fiber. ...
The link between the vaginal microbiome and pregnancy outcomes is so strong that someone’s vaginal microbiome can actually be used to predict IVF success What is the vaginal microbiome? ...
ByJuno Bio
The Use of Microbiome Sequencing in Cancer Research A growing body of evidence now suggests that human microbial dysbiosis has a crucial role in cancer development and progression. ...
It is often thought of as being what is in the gut of an animal when in reality the microbiome in the gut is just a small piece of a much larger microbiome. ...
With rapid development in sequencing technology, researchers can better assess the effect of the gut microbiome on human health. Human beings have a symbiotic relationship with the microbiota since birth. ...
Human microbiomics, therefore, is likely to be the next hotspot in precision medicine. Research Achievements of Human Microbiome In recent years, with the continuous research on the human microbiome, gut microbes have been found to be closely related to a variety of human diseases, including not only digestive tract diseases ...
The gut is a complex ecosystem that contains an extremely large community of microbes known as the gut microbiome. The gut microbiome is made up of bacteria, archaea, viruses, fungi, and other eukaryotic microorganisms, including yeasts, flagellates, ciliates, and protozoa. ...
Differences observed in the various gut regions contribute to and are impacted by the different bacterial ecosystems they contain. ...
This is simply because obtaining biopsies from a large portion of the gut is not accessible by routine endoscopy or colonoscopy. A simple illustration of this is issue is conventional modeling of cystic fibrosis (CF) in 3D gut tissue culture. ...
Advanced models of the gut leveraging intestinal and colonic stem cells are enabling the development of more reliable and robust systems for evaluating the impact of changes in the microbiome on gut health and screening potential drug candidates, including small molecules, biologics, and live biotherapeutics. ...
These results indicate that fibrosis severity rather than necroinflammatory activity is more likely associated with the changes of gut microbiome and underlying BMI status may also be an important factor responsible for alterations of the gut microbiome. ...
Symberix co-founder Matt Redinbo also published a research article in PNAS in March 2020 describing microbiota-targeted therapeutics that inhibit gut bacterial β-glucuronidases to enhance anticancer drug efficacy. Symberix, Inc. is a biopharmaceutical company focused on developing the first generation of gut microbiome-targeting drugs to ...
MedBiome’s founders reported in Microbiome the development of the RapidAIM platform to screen compounds against individual microbiomes in vitro. They tested 43 compounds (including 4 antibiotics) against 5 individual microbiomes using the RapidAIM technology. The RapidAIM workflow provides insights into microbiome absolute abundance and functional responses to ...
Researchers at the University of North Carolina at Chapel Hill have come up with a compound that could target the enzymes without disrupting the microbiome — a potential treatment for the diarrhoea. And their spin-off company, Symberix, is developing treatments to reduce side effects caused by gut ...
Abstract Gut microbiota play an important role in immune responses and energy metabolism. ...