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Hepatitis A Virus Articles & Analysis
15 articles found
One notable example is the use of the hepatitis B virus surface antigen. By inserting the relevant gene into yeast, large quantities of this antigen can be produced, which can then be purified and used in the vaccine formulation. ...
Currently, recombinant protein vaccines have been widely used in various infectious diseases, such as the prevention of hepatitis B virus (i.e., hepatitis B), tetanus, pertussis, influenza, etc.Monosaccharides are the simplest form of sugars, including glucose, fructose, galactose, etc. ...
The first combination of a TLR agonist and an aluminum adjuvant in an approved vaccine for human use was AS04, which consists of 3-O-deacetyl-4′-monophosphoryl lipid a (MPL) adsorbed on aluminum, and which is used in two GSK-developed vaccines, Cervarix and Fendrix, for the prevention of human papilloma virus (HPV) and hepatitis B virus ...
One target is the influenza hemagglutinin (HA), a glycoprotein family that allows the virus to enter host cells. To mitigate sequence diversity, vaccine design focuses on highly conserved domains, especially those targeted by broadly neutralizing antibodies on viral envelope glycoproteins. Due to the high conservation of the backbone region of HA2, it represents an excellent ...
Both approaches are compromised by the fast appearance of new virus variants escaping the preventive and therapeutic measures. The coronavirus disease 2019 (COVID-19) pandemic has clearly demonstrated the need for broad-spectrum antiviral drugs that are effective in treating more than just one specific virus variant, virus species, or phylum. ...
The occurrence of liver cancer is a very complex process, controlled by a variety of risk factors, including hepatitis B virus and hepatitis C virus infection, alcohol abuse, non-alcoholic fatty liver, genetic mutations, and long-term exposure to aflatoxin. ...
Much like the discovery of Sf-rhabdovirus at Takeda, this group serendipitously discovered TnCLV when they infected High Five™ cells (a Tn cell line) with a recombinant baculovirus encoding the hepatitis E capsid protein. They found these cells produced not only the expected baculovirus and hepatitis E virus-like particles, but also... ...
National emergency department (ED) visit prevalence and costs for selected diseases that can be transmitted by water were estimated using large healthcare databases (acute otitis externa, campylobacteriosis, cryptosporidiosis, Escherichia coli infection, free-living ameba infection, giardiasis, hepatitis A virus (HAV) infection, Legionnaires’ disease, ...
We selected 13 pathogens or syndromes implicated in waterborne disease outbreaks or other well-documented waterborne transmission (acute otitis externa, Campylobacter, Cryptosporidium, Escherichia coli (E. coli), free-living ameba, Giardia, Hepatitis A virus, Legionella (Legionnaires' disease), nontuberculous mycobacteria (NTM), Pseudomonas-related pneumonia or ...
Hepatitis E virus (HEV) is transmitted via the fecal–oral route and has been recognized as a common source of large waterborne outbreaks involving contaminated water in developing countries. ...
Hepatitis A virus (HAV) strains found in selected South African (SA) surface waters were characterised to establish what HAV types are circulating in the environment, thus reflecting circulation in the surrounding communities. ...
The main objective of this study was to determine the genomic copy concentrations of human adenoviruses F and G, Rotavirus (RV), Hepatitis A virus (HAV), Hepatitis E virus (HEV) and human adenovirus species A,C,D,E, and F (HAdV-ACDEF) in Bwaise III, a typical slum in Kampala, Uganda. Forty-one samples from surface water, grey ...
The antimicrobial activity of simulated solar disinfection (SODIS) against enteric waterborne viruses including coxsackievirus-B5, poliovirus-2 and hepatitis A virus was investigated in this study. Assays were conducted in transparent 12-well polystyrene microtitre plates containing the appropriate viral test suspension. ...
Hepatitis E virus (HEV) is a common cause of water-borne acute hepatitis in areas with poor sanitation. ...
Additionally, to date there are no vaccines or antiviral drugs for most common enteric and respiratory viruses with the exception of influenza virus and hepatitis A virus (HAV). Consequently, viral disease spread is most effectively deterred by preclusion of viral ...