Refine by
Hepatitis B Virus Articles & Analysis
15 articles found
One notable example is the use of the hepatitis B virus surface antigen. By inserting the relevant gene into yeast, large quantities of this antigen can be produced, which can then be purified and used in the vaccine formulation. ...
Currently, recombinant protein vaccines have been widely used in various infectious diseases, such as the prevention of hepatitis B virus (i.e., hepatitis B), tetanus, pertussis, influenza, etc.Monosaccharides are the simplest form of sugars, including glucose, fructose, galactose, etc. ...
In addition, dendritic cells can recruit aluminum-adsorbed antigen-antibody complexes, and complement factors can modulate receptors on B cells to form aluminum-adsorbed antigen-antibody complexes, thereby promoting immune responses. ...
Introduction to Microbial Epigenetics Epigenetics has been defined as the study of stable alterations in gene expression potentials that arise during development and cell proliferation, or alterations in DNA function without alterations in DNA sequence. Modern epigenetic features refer to the alteration of DNA and/or associated proteins without nucleotide sequence variance, which transmits the ...
Vero cellsare a continuous adherent cell line that is frequently used in cell culture and plays an important role in worldwide vaccine and vector production (manufacturing). Unlike other mammalian cells, they do not secrete interferon alpha or beta when infected by viruses – this is one of the reasons that efficient replication of many viruses can be achieved in Vero cells, ...
ByNuvonis
The lengthy battle between people and varied bodily, chemical, and organic insults that trigger cell damage (e.g., merchandise of tissue harm, metabolites, and/or infections) have led to the evolution of assorted adaptive responses. These responses are triggered by recognition of damage-associated molecular patterns (DAMPs) and/or pathogen-associated molecular patterns (PAMPs), normally by cells ...
The occurrence of liver cancer is a very complex process, controlled by a variety of risk factors, including hepatitis B virus and hepatitis C virus infection, alcohol abuse, non-alcoholic fatty liver, genetic mutations, and long-term exposure to aflatoxin. ...
Here we show that SRSF3 is decreased in human liver samples with nonalcoholic fatty liver disease (NAFLD), nonalcoholic steatohepatitis (NASH), or cirrhosis that was associated with alterations in RNA splicing of known SRSF3 target genes. Hepatic SRSF3 expression was similarly decreased and RNA splicing dysregulated in mouse models of NAFLD and NASH. ...
Much like the discovery of Sf-rhabdovirus at Takeda, this group serendipitously discovered TnCLV when they infected High Five™ cells (a Tn cell line) with a recombinant baculovirus encoding the hepatitis E capsid protein. They found these cells produced not only the expected baculovirus and hepatitis E virus-like particles, but also... ...
Hepatitis E virus (HEV) is transmitted via the fecal–oral route and has been recognized as a common source of large waterborne outbreaks involving contaminated water in developing countries. Thus, there is the need to produce experimental data on the disinfection kinetics of HEV by chlorine in water samples with diverse levels of fecal contamination. Here, the inactivation of HEV and ...
Hepatitis A virus (HAV) strains found in selected South African (SA) surface waters were characterised to establish what HAV types are circulating in the environment, thus reflecting circulation in the surrounding communities. Surface water samples used for irrigation or domestic purposes, and water samples from the outflow of wastewater plants were collected from six provinces. Viruses were ...
The presence of viruses in a slum environment where sanitation is poor is a major concern. However, little is known of their occurrence and genomic copy concentration in the slum environment. The main objective of this study was to determine the genomic copy concentrations of human adenoviruses F and G, Rotavirus (RV), Hepatitis A virus (HAV), Hepatitis E virus (HEV) and human adenovirus ...
The antimicrobial activity of simulated solar disinfection (SODIS) against enteric waterborne viruses including coxsackievirus-B5, poliovirus-2 and hepatitis A virus was investigated in this study. Assays were conducted in transparent 12-well polystyrene microtitre plates containing the appropriate viral test suspension. Plates were exposed to simulated sunlight at an optical irradiance of 550 ...
Hepatitis E virus (HEV) is a common cause of water-borne acute hepatitis in areas with poor sanitation. In 2004 an outbreak of HEV infection affected around 2,000 people in Eastern Chad (Dar Sila). This paper describes the decrease in the incidence of acute jaundice syndrome (AJS) from 2004 until 2009 when a mean incidence of 0.48 cases/1,000 people/year was recorded in the region. Outbreaks of ...
Worldwide annually there are 1.7 million deaths from diarrheal diseases and 1.5 million deaths from respiratory infections (56). Viruses cause an estimated 60% of human infections, and most common illnesses are produced by respiratory and enteric viruses (7, 49). Unlike bacterial disease, viral illness cannot be resolved with the use of antibiotics. Prevention and management of viral disease ...