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Hepatitis E Virus Articles & Analysis
16 articles found
The field of immunology has experienced significant advancements over recent years, particularly in the area of recombinant vaccine production. This innovative approach has revolutionized the way vaccines are developed, manufactured, and administered, offering a promising alternative to traditional methods. By utilizing recombinant DNA technology, scientists can produce vaccines that are more ...
Recombinant protein vaccine is a type of vaccine that does not contain complete pathogens and is prepared from specific protein antigens produced by heterologous expression systems. Due to their advantages of good safety, strong stability, and relatively low cost, recombinant protein vaccines have been widely favored by researchers in recent years. Currently, recombinant protein vaccines have ...
Introduction to Microbial Epigenetics Epigenetics has been defined as the study of stable alterations in gene expression potentials that arise during development and cell proliferation, or alterations in DNA function without alterations in DNA sequence. Modern epigenetic features refer to the alteration of DNA and/or associated proteins without nucleotide sequence variance, which transmits the ...
Vero cellsare a continuous adherent cell line that is frequently used in cell culture and plays an important role in worldwide vaccine and vector production (manufacturing). Unlike other mammalian cells, they do not secrete interferon alpha or beta when infected by viruses – this is one of the reasons that efficient replication of many viruses can be achieved in Vero cells, ...
ByNuvonis
The lengthy battle between people and varied bodily, chemical, and organic insults that trigger cell damage (e.g., merchandise of tissue harm, metabolites, and/or infections) have led to the evolution of assorted adaptive responses. These responses are triggered by recognition of damage-associated molecular patterns (DAMPs) and/or pathogen-associated molecular patterns (PAMPs), normally by cells ...
Liver cancer is the fifth most common cancer in the world and the third leading cause of cancer deaths. A healthy diet and lifestyle are the key to preventing various diseases. In recent years, probiotics, as part of a healthy diet, have received increasing attention for their role in cancer prevention and treatment, including liver cancer. Do probiotics have the potential to prevent liver ...
Abstract Serine-rich splicing factor 3 (SRSF3) plays a critical role in liver function and its loss promotes chronic liver damage and regeneration. As a consequence, genetic deletion of SRSF3 in hepatocytes caused progressive liver disease and ultimately led to hepatocellular carcinoma. Here we show that SRSF3 is decreased in human liver samples with nonalcoholic fatty liver disease (NAFLD), ...
Much like the discovery of Sf-rhabdovirus at Takeda, this group serendipitously discovered TnCLV when they infected High Five™ cells (a Tn cell line) with a recombinant baculovirus encoding the hepatitis E capsid protein. They found these cells produced not only the expected baculovirus and hepatitis E ...
National emergency department (ED) visit prevalence and costs for selected diseases that can be transmitted by water were estimated using large healthcare databases (acute otitis externa, campylobacteriosis, cryptosporidiosis, Escherichia coli infection, free-living ameba infection, giardiasis, hepatitis A virus (HAV) infection, Legionnaires’ disease, nontuberculous mycobacterial (NTM) ...
We selected 13 pathogens or syndromes implicated in waterborne disease outbreaks or other well-documented waterborne transmission (acute otitis externa, Campylobacter, Cryptosporidium, Escherichia coli (E. coli), free-living ameba, Giardia, Hepatitis A virus, Legionella (Legionnaires' disease), nontuberculous mycobacteria (NTM), ...
Hepatitis E virus (HEV) is transmitted via the fecal–oral route and has been recognized as a common source of large waterborne outbreaks involving contaminated water in developing countries. ...
Hepatitis A virus (HAV) strains found in selected South African (SA) surface waters were characterised to establish what HAV types are circulating in the environment, thus reflecting circulation in the surrounding communities. Surface water samples used for irrigation or domestic purposes, and water samples from the outflow of wastewater plants were collected from six provinces. Viruses were ...
The main objective of this study was to determine the genomic copy concentrations of human adenoviruses F and G, Rotavirus (RV), Hepatitis A virus (HAV), Hepatitis E virus (HEV) and human adenovirus species A,C,D,E, and F (HAdV-ACDEF) in Bwaise III, a typical slum in Kampala, Uganda. Forty-one ...
The antimicrobial activity of simulated solar disinfection (SODIS) against enteric waterborne viruses including coxsackievirus-B5, poliovirus-2 and hepatitis A virus was investigated in this study. Assays were conducted in transparent 12-well polystyrene microtitre plates containing the appropriate viral test suspension. Plates were exposed to simulated sunlight at an optical irradiance of 550 ...
Hepatitis E virus (HEV) is a common cause of water-borne acute hepatitis in areas with poor sanitation. ...
Worldwide annually there are 1.7 million deaths from diarrheal diseases and 1.5 million deaths from respiratory infections (56). Viruses cause an estimated 60% of human infections, and most common illnesses are produced by respiratory and enteric viruses (7, 49). Unlike bacterial disease, viral illness cannot be resolved with the use of antibiotics. Prevention and management of viral disease ...