hiv infection Articles
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Water, sanitation and hygiene practice and associated factors among HIV infected people in Arba Minch town, Southern Ethiopia
Human immunodeficiency virus (HIV) infected people have substantially greater need for water, sanitation and hygiene (WASH). Many opportunistic infections cause high morbidity and mortality in people living with HIV (PLHIV) than in immune competent populations. The objective of the study was to assess WASH practices and associated factors among PLHIV. A cross-sectional study design was ...
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Anti-HIV and anti-inflammatory action of iodine-lithium-α-dextrin is accompanied by the improved quality of life in AIDS patients
Clinical efficacy, tolerability and safety of various doses of Iodine-Lithium-α-Dextrin (ILαD) monotherapy have been evaluated in 56 HIV-infected patients enrolled in double blind uncontrolled randomised study during 48 weeks follow-up period. ILαD was administered intravenously three times over five days with intervals of 23 weeks between treatments for a total of 12 infusions in 4 cycles. HIV-1 ...
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Comparative effect of an immunomodulator Immunoxel (DzhereloT) when used alone or in combination with antiretroviral therapy in drug-naive HIV-infected individuals
Immunomodulating agent Immunoxel (Dzherelo) has been evaluated in 70 HIV-positive individuals divided into three arms: first, control arm, received standard antiretroviral therapy zidovudine/lamivudine/efavirenz (AZT7/3TC/EFV); second-AZT/3TC/EFV+Immunoxel and third, Immunoxel alone, given orally, twice daily. At 32 weeks of follow-up CD4 cell counts increased in all arms, reaching + 102, +190 ...
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The role of educational institutions in combating HIV/AIDS in Africa
The rate and number of HIV/AIDS infection in Africa is alarming and worsening. The design of effective prevention strategies hinges on an understanding of the multifaceted causes of the pandemic, or its regional epidemic. On this score, the role of educational institutions becomes imperative. This paper will examine available data to guage the enormity and urgency of the HIV/AIDS epidemic in ...
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UVC helps cut heating costs in jails
If you think it’s hard to get HVAC money for schools and similar public buildings, there is a harder nut to crack: correctional facilities. It can be even more difficult to get additional funds appropriated to improve conditions in buildings where people are incarcerated. Compounding the problem, many correctional facility employees are in close proximity with the inmate community daily. ...
By E-CO
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Engineering of a human vaginal lactobacillus strain for surface expression of two-domain cd4 molecules
Women are at significant risk of heterosexually transmitted human immunodeficiency virus (HIV) infection, with the mucosal epithelium of the cervix and vagina serving as a major portal of entry. The cervicovaginal mucosa naturally harbors dynamic microflora composed predominantly of lactobacilli, which may be genetically modified to serve as a more efficient protective barrier against the ...
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Scientists successfully unraveled the lifecycle of HIV
Despite being recently covered by the global epidemic of COVID-19, humanity is still facing an epidemic of another disease, AIDS, with approximately 38 million people living with HIV worldwide, according to UNAIDS. Many people have died as a result of HIV infection since the epidemic began in the 1980s. Researchers from Germany have recently developed a new technique that may be able to ...
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HIV-1 subtype C vaccine: waiting in wings for the human trials
India has more than 5 million people infected with HIV-1 and this number is likely to increase in coming years. It is estimated that by the turn of this decade more than 10 million people would have been infected with this virus. More than 90% of these infections are due to subtype C. Therefore, it is imperative that a vaccine be developed based on local circulating subtype and tested for ...
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RVx201 Herpes Vaccine
RVx201 Herpes Vaccine Description 2022 RVx201 is a first-in-human herpes simplex virus type 2 (HSV-2) live-attenuated therapeutic vaccine modified to be interferon sensitive that destroys the ability of the virus to inhibit immune responses. Produced by Rational Vaccines, Inc., the technology is based on the pioneering research of the late Dr. William Halford, who dedicated over 25 years to ...
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The 3rd AIDS patient is "cured"! Has mankind finally conquered AIDS?
At an academic conference on Feb 15, U.S. experts announced the world's first female AIDS "cure," making it the third case of HIV infection to be cured. After therapy and withdrawal of antiviral drugs, HIVs were not identified in the patient's body for more than 14 months, indicating that the virus was in complete remission, according to academics. The key to this patient's recovery was a blood ...
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Troubling Health Trends Holding Back Progress on Life Expectancy
People born today will live for 68 years on average, 20 years longer than those born in 1950. By the mid-twentieth century, industrial countries had already made major strides in extending lifespans with improvements in sanitation, nutrition, and public health. After World War II, rapid gains in life expectancy in developing countries began to narrow the gap between these nations and industrial ...
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Leadership for Results in tackling HIV/AIDS
Integral sustainability theory is evident in the UN’s approach to tackling HIV/AIDS in various locations around the world. The approach focuses on a range of change activities that reference a multi-dimensional view of the issue. Business insight HIV/AIDS is a global epidemic but is most acute in some of the poorest regions on earth. It is compounded by a range of issues including ...
By Article 13
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Needlestick Injury - the pointy end of a preventable pandemic
The Challenge Every 60 minutes, of every day, six people suffer a needlestick injury somewhere in the world. Every day, 3 people die as a result of those injuries[1]. The World Health Organisation (WHO) reports in the World Health Report 2002, that of the 35 million health-care workers world wide, two million experience percutaneous exposure to infectious diseases each year[2]. WHO estimates ...
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World Immunization Week: Taming Latent Viruses for Longer Lives
The World Health Organization created World Immunization Week to highlight global collective action and promote the use of vaccines that keep all of us protected against disease. This year, the theme is “Long Life for All: In pursuit of a long life well lived.” The COVID-19 pandemic demonstrated the criticality of mRNA vaccines as a tool for quickly and effectively battling ...
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Understanding the Workflow and Practical Applications of Drug Affinity Responsive Target Stability (DARTS)
Introduction of Drug Affinity Responsive Target Stability (DARTS) Drug target protein identification is an important step in the research and development of new drugs. Drug Affinity Response Target Stability (DARTS) is a technique that can rapidly and directly identify potential target proteins of small molecule drugs. That is, it prevents the target protein from being hydrolyzed by proteases ...
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What are Strongyloides?
Strongyloides is an opportunistic pathogenic parasitic nematode. Adults parasitize in the small intestine of cats, dogs and humans. The larvae can invade lung, brain, liver, kidney and other tissues and organs, causing strongyloidiasis. The disease is mainly prevalent in warm and humid tropical and subtropical regions. In recent years, due to the continuous increase of HIV/AIDS infection rate in ...
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Peptide Vaccine Design
Vaccines are considered one of the most successful medical interventions in the past few centuries, aiming to harness the human immune system and generate lasting protection against specific diseases. Traditional vaccines rely on the use of inactivated pathogens to trigger an immune response. However, many of these formulations carry a high risk of causing allergies or autoimmune reactions. ...
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Toxic black mold – The deadly Myth
If you have ever been in a damp, musty basement, chances are you were exposed to elevated levels of mold. Many of us have seen that little line of greenish black coating near a bathroom tub or window. In case you haven’t guessed it yet, that’s more than likely mold. What happens next – do you vacate the home – is it dangerous – what if I have kids. First, don’t ...
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Prevent hospital acquired infections during construction projects
The issue of hospital acquired infections is a serious problem. According to several sources, three to four million hospital-acquired infections occur annually, with up to 80,000 fatalities. The costs of these infections are estimated to be between $4 billion and $5 billion per year (Air-Treatment Systems for Controlling Hospital acquired Infections, HPAC Engineering, April 2, 2008).Healthcare ...
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What is FGL2?
Inflammation is a series of complex response events produced by the host system to pathogen infection and various tissue injuries. When the inflammatory response continues, it enters the stage of "uncontrollable inflammation", which plays an important role in the occurrence and development of complex diseases such as tumors. Therefore, the key molecular events in the process of ...
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