Hpv Articles & Analysis: Older
13 articles found
Applications and Functions of Cancer Vaccines Cancer vaccines serve several purposes in oncology. For illustration, the HPV vaccine helps prevent cervical cancer by targeting the human papillomavirus. ...
What Is RNA Splicing? RNA splicing is a post-transcriptional modification process that occurs in eukaryotic cells. When a gene is transcribed, the initial RNA product is called pre-mRNA, which contains both coding regions (exons) and non-coding regions (introns). RNA splicing removes the introns from the pre-mRNA molecule and joins together the exons to form a mature mRNA molecule that can be ...
The first combination of a TLR agonist and an aluminum adjuvant in an approved vaccine for human use was AS04, which consists of 3-O-deacetyl-4′-monophosphoryl lipid a (MPL) adsorbed on aluminum, and which is used in two GSK-developed vaccines, Cervarix and Fendrix, for the prevention of human papilloma virus (HPV) and hepatitis B virus (HBV), respectively. MPL is a ...
One method is introduction of a viral gene that partially deregulates the cell cycle, such as EBV, SV40 T antigens and HPV-16 E6/7 gene. The cellular gene encoding human telomerase reverse transcriptase (hTert) has been successfully used for the expansion of several cell types that retain important properties in vitro. ...
Introduction to Microbial Epigenetics Epigenetics has been defined as the study of stable alterations in gene expression potentials that arise during development and cell proliferation, or alterations in DNA function without alterations in DNA sequence. Modern epigenetic features refer to the alteration of DNA and/or associated proteins without nucleotide sequence variance, which transmits the ...
That includes viruses like Human Papillomavirus (HPV). What is HPV? HPV is a viral infection most commonly acquired sexually… In fact, it’s the most common STI. ...
ByJuno Bio
HPV-16 E7-Specific Cellular Immune Response in Women With Cervical Intraepithelial Lesion Contributes to Viral Clearance: A Cross-Sectional and Longitudinal Clinical Study High-risk human papillomavirus (HPV) infection is the cause of almost all cervical cancers. ...
Studying the vaccine in dogs could provide insight into its effectiveness in people What if someone told you that a vaccine shot could prevent you from getting multiple types of cancer—ones as different from each other as breast cancer and lymphoma? Stephen A. Johnston, cofounder of the health-care start-up Calviri and a scientist at Arizona State University’s Biodesign Institute, ...
ByCalviri
Cervical cancer is caused by the Human Papilloma Virus or HPV. The lower part of the uterus known as Cervix is affected due to HPV infection. ...
Abstract Phase I clinical trials are the first step in drug development to test a new drug or drug combination on humans. Typical designs of Phase I trials use toxicity as the primary endpoint and aim to find the maximum tolerable dosage. However, these designs are poorly applicable for the development of cancer therapeutic vaccines because the expected safety concerns for these vaccines are not ...
As a developing nation, Vietnam's government must balance many, competing interests in implementing a public health intervention and encourage collaboration among various stakeholders, while also acknowledging and harmonising their individual interests.Keywords: Vietnam, human papillomavirus, HPV, patents, vaccines, pap test, cervical cancer, health disparities, intellectual ...
Transcription of the catalytic subunit of telomerase (hTERT) in keratinocytes can be induced by human papillomavirus type 16 (HPV16) E6/E6AP ubiquitin ligase through degradation of the repressor, NFX1-91. Here, we demonstrate that NFX1-91 interacts with the corepressor complex mSin3A/histone deacetylase (HDAC) at the hTERT promoter. By degrading NFX1-91, E6/E6AP changes the chromatin structure at ...
EPA recently posted on its Chemical Right-to-Know website a new policy, entitled Policy Regarding Acceptance of New Commitments to the High Production Volume (HPV) Challenge Program, available at www.epa.gov/chemrtk/hpvpolcy.pdf. The policy outlines how companies can commit to sponsor any of the remaining so-called “orphan chemicals,” which include the 300 chemicals that are ...