human immunodeficiency virus Articles
-
Risky (legal) business: HIV and criminal culpability in Victoria
This article examines HIV transmission jurisprudence in the Australian state of Victoria. It details the development of criminal legislation to respond to the issue of HIV and the application of these offences to prosecute charges of HIV transmission in Victoria. It also outlines the case law in Victoria. The article questions the juridical handling of consensual sexuality and HIV risk, within ...
-
Rationalising fixed dose combinations for tuberculosis and acquired immunodeficiency syndrome therapy
Poorly managed healthcare can be directly attributed to extensive drug regimens. Numerous chronic illnesses and epidemics such as HIV/AIDS and tuberculosis require elaborate drug regimens for efficacious therapeutic outcomes. Various drug delivery systems have been developed to simplify their regimental drug therapy. However, more effective and innovative drug delivery technologies are required ...
-
Expression quantitative trait locus mapping of toxoplasma genes reveals multiple mechanisms for strain-specific differences in gene expression
Toxoplasma gondii is an intracellular parasite with a significant impact on human health, especially in cases where individuals are immunocompromised (e.g., due to human immunodeficiency virus/AIDS). In Europe and North America, only a few clonal genotypes appear to be responsible for the vast majority of Toxoplasma infections, and these clonotypes have been intensely studied to identify ...
-
Water, sanitation and hygiene practice and associated factors among HIV infected people in Arba Minch town, Southern Ethiopia
Human immunodeficiency virus (HIV) infected people have substantially greater need for water, sanitation and hygiene (WASH). Many opportunistic infections cause high morbidity and mortality in people living with HIV (PLHIV) than in immune competent populations. The objective of the study was to assess WASH practices and associated factors among PLHIV. A cross-sectional study design was ...
-
Preclinical and safety studies of V-1 Immunitor
The safety of V-1 Immunitor (V1) has been investigated. L929; BHK; Vero; Caco-2 and CEM-SS cells have not shown cytotoxicity even at 10 mg/ml dose. Ames' mutagenicity and micronucleus genotoxicity tests came out negative at 50 mg and 2000 mg/kg doses in Salmonella and bone marrow of IRC mice. Acute and chronic dosing of V1 to Swiss albino mice and Spague Dawley rats failed to cause any deaths. ...
-
Engineering of a human vaginal lactobacillus strain for surface expression of two-domain cd4 molecules
Women are at significant risk of heterosexually transmitted human immunodeficiency virus (HIV) infection, with the mucosal epithelium of the cervix and vagina serving as a major portal of entry. The cervicovaginal mucosa naturally harbors dynamic microflora composed predominantly of lactobacilli, which may be genetically modified to serve as a more efficient protective barrier against the ...
-
Needlestick Injury - the pointy end of a preventable pandemic
The Challenge Every 60 minutes, of every day, six people suffer a needlestick injury somewhere in the world. Every day, 3 people die as a result of those injuries[1]. The World Health Organisation (WHO) reports in the World Health Report 2002, that of the 35 million health-care workers world wide, two million experience percutaneous exposure to infectious diseases each year[2]. WHO estimates ...
-
Understanding the Workflow and Practical Applications of Drug Affinity Responsive Target Stability (DARTS)
Introduction of Drug Affinity Responsive Target Stability (DARTS) Drug target protein identification is an important step in the research and development of new drugs. Drug Affinity Response Target Stability (DARTS) is a technique that can rapidly and directly identify potential target proteins of small molecule drugs. That is, it prevents the target protein from being hydrolyzed by proteases ...
Need help finding the right suppliers? Try XPRT Sourcing. Let the XPRTs do the work for you