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Human Immunodeficiency Virus Hiv Infection Articles & Analysis

2 articles found

Understanding the Workflow and Practical Applications of Drug Affinity Responsive Target Stability (DARTS)

Understanding the Workflow and Practical Applications of Drug Affinity Responsive Target Stability (DARTS)

Gong et al. also demonstrated that DCA can lead to abnormal aggregation of reactive oxygen species (ROS) through histone D (CTSD) and thioredoxin-like protein 1 (TXNL1), and that Akt-mTOR, the most important negative regulatory pathway for autophagy, is inhibited. 3. Identification of the anti-HIV targets of ratjadone A Fleta-Soriano et al. found that Ratjadone A, a ...

ByCreative Proteomics


Engineering of a human vaginal lactobacillus strain for surface expression of two-domain cd4 molecules

Engineering of a human vaginal lactobacillus strain for surface expression of two-domain cd4 molecules

Women are at significant risk of heterosexually transmitted human immunodeficiency virus (HIV) infection, with the mucosal epithelium of the cervix and vagina serving as a major portal of entry. The cervicovaginal mucosa naturally harbors dynamic microflora composed predominantly of lactobacilli, which may be ...

ByAmerican Society for Microbiology (ASM)

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