Human Natural Vascular Scaffolding Clinical Trial Articles & Analysis
18 articles found
Rare diseases, also known as orphan diseases, are a diverse group of disorders that affect a small percentage of the population. Due to their low prevalence and limited understanding, treating and finding cures for these conditions present significant challenges. However, preclinical animal models have emerged as invaluable resources for advancing research and unraveling the mysteries surrounding ...
In the world of pharmaceuticals, developing safe and effective drugs is a complex and time-consuming process. Before a new drug candidate can progress to clinical trials and ultimately reach the market, it needs to undergo rigorous testing in various model systems to assess its efficacy and safety. One critical component of this evaluation is the use of preclinical animal models. Preclinical ...
Health research is very important for improving health care for all. As we mentioned in a previous article, What is Health Research?, this type of research helps medical researchers understand people’s health and how we can make treatments better for everyone. But health research isn’t possible without the contributions of research participants. Research participants are ...
Schistosomiasis is a major neglected tropical disease (NTD) of public health concern to a billion people. Currently an estimated 200 million are infected and an additional an estimated 800 million people are at risk of acquiring this disease in 74 countries. The disease carries high morbidity. Revised estimates of disability adjusted life years (DALYs) and recent calculations based on ...
The World Health Organization in its report on Neglected Tropical Diseases has stated that there is overwhelming evidence to show that the burden caused by many of the 17 diseases that affect more than 1 billion people worldwide can be effectively controlled and, in many cases, eliminated or even eradicated. Leishmaniasis caused by Leishmania spp is one such example and poses a grave health risk ...
SmartTab is pioneering a wireless remote controlled drug delivery system, has completed pre-clinical animal studies and is preparing for human clinical trials for its core technology TargetTab™. This proprietary and patented wireless capsule will revolutionize targeted drug delivery and medicine adherence. DENVER, CO — Prescription pills are often delivered to the wrong site, at ...
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Recent molecular discoveries have provided new details on how Nipah and Hendra viruses attack cells, and the immune responses that fight back against this attack. The findings point to a multi-pronged strategy for preventing and treating these deadly diseases. The study was published in Science recently. Both Nipah virus and Hendra virus are carried by indigenous bats in some parts of the ...
January 6, 2022—Researchers at the Perelman School of Medicine at the University of Pennsylvania published a research paper in Science titled: CAR-T cells produced in vivo to treat cardiac injury. Heart damage or inflammation can induce fibroblasts to overproduce fibrous material, causing cardiac fibrosis, which hardens the heart muscle and impairs heart function. Heart failure, liver ...
Innovations and Iterations In the consumer tech world, iterations happen very fast, though most inventions are not ‘one and done’ masterpieces: the Dyson cyclone vacuum cleaner made 5,127 prototypes. In the medical device world, development takes longer because of the appropriate and necessary regulations and need for safety. Using an agile approach, but with safety and reliability ...
Due to a lack of robust in vivo gut models, animal studies are generally required to evaluate gut toxicity. However, these studies can be lengthy and expensive and may not accurately recapitulate the behavior of the human gastrointestinal tract. Drugs are thus often developed with undesired gut side effects that are not apparent until clinical trials. Organ-on-a-chip models are the closest ...
Myles Greenberg describes this exciting new technology and the path to patients, with first-in-human clinical trials launching earlier this year. What is the story behind the technology? ...
MADISON, Wis.–(BUSINESS WIRE)–An international collaboration of virologists at the University of Wisconsin–Madison and the vaccine companies FluGen and Bharat Biotech has begun the development and testing of a unique vaccine against COVID-19 called CoroFlu. UW–Madison, FluGen, Bharat Biotech to develop CoroFlu, a coronavirus vaccineTweet this CoroFlu will build on the ...
The enzyme-linked immunosorbent spot (ELISpot) assay is one of the most commonly used methods to measure antigen-specific T cells in both mice and humans. Some of the primary reasons for the popularity of the method are that ELISpot is highly quantitative, can measure a broad range of magnitudes of response and is capable of assessing critical cellular immune-related activities such as IFN-g ...
A team of Jerusalem-based researchers and entrepreneurs claim they have a cure for diabetesthat could hit the market as early as within the next few years. Betalin Therapeutics has developed the first bio-artificial pancreas, composed of pig’s lung tissue and insulin secreting cells. The artificial pancreas would be implanted into the patient and connect with his or her blood vessels, ...
Editor’s note: Startland selected 12 Kansas City firms to spotlight for its annual Startups to Watch list. The following is one of 2019’s companies. Click here to view the full, ranked list of Startups to Watch. Metactive’s elevator pitch: Medical tech company that makes catheter-based devices used to treat cardiovascular disease, stroke, cancer, and life-threatening bleeding. ...
It’s no secret that opioid addiction is at an all-time high and represents a major public health threat. The CDC estimates that opioid addiction resulted in a record 72,000 drug overdose deaths in 2017 alone. What strikes me as one of the most tragic parts of this narrative is that so many of these deaths were people who became addicted to opioids after simply seeking relief ...
We have developed a cell culture-derived, inactivated bivalent vaccine against both Haemorrhagic Fever with Renal Syndrome (HFRS) viruses 84 Fli (type I) and L99 (type II). This purified vaccine was tested in the clinical phase I/II trial in healthy non-infected adults in China. About 518 volunteers in Southern region and 650 volunteers from the Northern region of China were vaccinated. ...
Xenotransplantation (XTP) involves the transplantation of cells, tissues and organs from non-human mammals (usually pigs) to humans. Because XTP could produce considerable public health gains, advocates want to proceed to human clinical trials as soon as possible. However, XTP also raises complex regulatory issues, since virtually all scientists agree that there is a risk of pig endogenous ...