Human Plasma Proteome Articles & Analysis
3 articles found
Transmembrane protein receptors and other targets account for 20-30% of the human proteome and 60% of current drug targets. However, due to the complex multi-structure, large conformational variation, low immunogenicity, and lack of soluble forms of transmembrane receptors, it is difficult to develop functional antibodies against these receptors.2. ...
In the vast and ever-evolving field of medicine, the discovery of new drugs has been a critical pursuit, offering hope and relief to countless individuals suffering from various ailments. The process of drug discovery is a complex and multifaceted endeavor, involving the integration of diverse scientific disciplines, including biology, chemistry, and computational science. At the heart of this ...
Mitochondria are important organelles of eukaryotic cells and play a key role in the regulation of cellular energy metabolism, biosynthesis and cell death (including apoptosis and programmed cell necrosis). In addition, mitochondria are involved in important physiological processes such as tricarboxylic acid cycle, fatty acid and amino acid oxidation, and regulation of calcium ion homeostasis. ...