Human Proteomics Articles & Analysis
3 articles found
Transmembrane protein receptors and other targets account for 20-30% of the human proteome and 60% of current drug targets. However, due to the complex multi-structure, large conformational variation, low immunogenicity, and lack of soluble forms of transmembrane receptors, it is difficult to develop functional antibodies against these receptors.2. ...
This involves understanding the specific biomolecular interactions between a drug and its intended target, often a protein or enzyme within the human body. By elucidating these interactions, researchers can gain valuable insights into the mechanisms by which a drug exerts its therapeutic effects. ...
With the development of mitochondrial proteome extraction, isolation and identification technologies, it is now possible to analyze both the entire mitochondrial proteome and to target membrane gap or matrix subregion interproteome analysis. Proteomics provides a wealth of mitochondrial gene and protein information that, when combined with ...