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Hypoxia Articles & Analysis

31 articles found

A New Approach to Respiratory Monitoring in Preclinical Research without restraint or acclimation

A New Approach to Respiratory Monitoring in Preclinical Research without restraint or acclimation

In preclinical respiratory studies, traditional methods like plethysmography often require animal restraint and extensive acclimation, limiting their ability to capture dynamic respiratory changes. To overcome these challenges, IPS Therapeutique Inc. validated a novel telemetry-based technique for continuous monitoring of intrapleural pressure and respiratory patterns in conscious, freely ...

BySCIREQ - an emka TECHNOLOGIES Company


Understanding Tumor Energy Metabolism through Glycolysis and Oxidative Phosphorylation   

Understanding Tumor Energy Metabolism through Glycolysis and Oxidative Phosphorylation  

Normal cells, in the presence of oxygen, rely mainly on OXPHOS to produce ATP, a process that provides 70% of the energy required for cellular metabolism. In contrast, it is under hypoxia that glycolytic activity is enhanced and used to compensate for the reduced OXPHOS function due to hypoxia. ...

ByCreative Proteomics


The Role of Orexin Neurons in Altered Respiratory Responses and SUDEP Risk

The Role of Orexin Neurons in Altered Respiratory Responses and SUDEP Risk

This blog delves into a fascinating study that investigates how altered ventilatory responses to hypercapnia-hypoxia (HH) challenges in a preclinical SUDEP model implicate orexin ...

Byemka Technologies S.A.S


Cubic Gas Sensing Solutions for Anesthesia Machines

Cubic Gas Sensing Solutions for Anesthesia Machines

In addition to monitoring EtCO2, closely tracking oxygen concentration could ensure that patient's breathing oxygen levels remain within a safe range during the surgical procedure, avoiding situations of oxygen toxicity or hypoxia. Cubic has specifically designed Gasboard-2510 oxygen sensor for accurate oxygen concentration measurement. ...

ByCubic Sensor and Instrument Co., Ltd


Unveiling the Role of CD73: A Key Player in Immune Regulation and Beyon

Unveiling the Role of CD73: A Key Player in Immune Regulation and Beyon

Annu Rev Immunol. (2019) 37:325–47. doi: 10.1146/annurev-immunol-051116-052406 [2] Bowser JL, Lee JW, Yuan X, Eltzschig HK. The hypoxia-adenosine link during inflammation. J Appl Physiol. (2017) 123:1303–20. doi: 10.1152/japplphysiol.00101.2017 [3] Bowser JL, Phan LH, Eltzschig HK. The hypoxia-adenosine link during intestinal inflammation. J Immunol. ...

ByBeta Lifescience


High-Altitude Low-Pressure Human Physiology Studies with the Hiden HPR-20 R&D

High-Altitude Low-Pressure Human Physiology Studies with the Hiden HPR-20 R&D

In the field of aviation and aerospace research, it’s crucial to understand how low-pressure, high-altitude conditions affect the human body. These studies can help ensure the safety and efficiency of flight and space crew selection and ...

ByHiden Analytical Ltd.


We put the O2 in WRKUT

We put the O2 in WRKUT

The explanation is simple: with prolonged and intense utilization of oxygen by the structures of the body, a phenomenon called hypoxia, meaning lack of oxygen, occurs in the internal environment of the body, causing accumulation of lactic acid, which leads to muscle sore. The effects of hypoxia do not stop here: by depleting the oxygen in the body, negative ...

ByOXYHELP INDUSTRY


Development of a Bioartificial Vascular Pancreas

Development of a Bioartificial Vascular Pancreas

In silico simulations and in vitro bioreactor experiments show that the BVP design provides adequate survivability for islets and helps avoid islet hypoxia. When implanted as end-to-end abdominal aorta grafts in nude rats, BVPs were able to restore near-normoglycemia durably for 90 days and developed robust microvascular infiltration from the host. ...

ByHumacyte, Inc.


An NBA Superstar and Sleep Apnea: Shaq

An NBA Superstar and Sleep Apnea: Shaq

Long-term damage to a patient can occur without treatment, including hypoxia, effects on memory, and an increased risk of heart disease and death. ...

ByBioSerenity


Vitamins: Types and Their Functions

Vitamins: Types and Their Functions

Vitamin B15 (Panganmic Acid): Eliminates hypoxia. It promotes the metabolism of proteins and stimulates the activity of the glandular nervous system. ...

ByCreative Proteomics


Importance of hemodynamic monitoring during esophagectomy - Case Study

Importance of hemodynamic monitoring during esophagectomy - Case Study

The patient had a difficult re-intubation that caused acute hypoxia and a compensatory increase in HR. Patient was re-positioned to left lateral, then the right lung was collapsed to allow access to and resection of the esophagus. ...

ByRetia Medical, LLC


How Reduced Oxygen Delivery Devices are Used in the Military

How Reduced Oxygen Delivery Devices are Used in the Military

The defence industry requires advanced technology and solutions for the unique, and often extreme conditions, in which people work. The military conducts scientific and technological research and officer training in high altitude environments with low oxygen levels. Thus, reduced oxygen delivery devices are necessary and widely used by various branches of the military, including the Air Force, ...

ByEnvironics, Inc.


FIGO good clinical practice paper: management of the second stage of labor

FIGO good clinical practice paper: management of the second stage of labor

Important potential complications arising in the second stage of labor are fetal hypoxia leading to birth asphyxia; failure of the presenting part to rotate or descend appropriately; and worsening or new maternal hypertension and pre-eclampsia. ...

ByMedinvent Ltd


InfraScan Inc. Announces Issuance of US Patents for Brain Diagnosis

InfraScan Inc. Announces Issuance of US Patents for Brain Diagnosis

"The latest patents make claims in connection with near-infrared technology that allows local hypoxia and edema detection in addition to hemorrhage detection,” said Baruch Ben Dor, PhD, president and CEO of InfraScan. ...

ByInfraScan, Inc.


COVID-19 Clinical Report for Dead Infected Case

COVID-19 Clinical Report for Dead Infected Case

The tract is blocked by mucus, and the clinical manifestation of hypoxia will occur. Therefore, to improve the human hypoxia and maintain the airway patency, the mucus must be diluted or dissolved. ...

ByBeijing Yaguo Technology Co., Ltd.


KTM - Save costs with self-produced medical oxygen

KTM - Save costs with self-produced medical oxygen

For example, oxygen is used in a number of operating theatres and to treat hypoxia in drug addicts in the Czech Republic‘s only detoxification centre. ...

ByInmatec GaseTechnologie GmbH & Co. KG


The Role of Lactate in Sepsis Research

The Role of Lactate in Sepsis Research

Studies have shown that an increase in lactate production is probably not due to hypoperfusion and hypoxia, but rather when sepsis is present lactate is produced partly as a response to beta-2 adrenergic receptors being stimulated, which then up-regulates glycolysis. ...

ByAnalox Instruments Ltd


Oxygen therapy for rheumatology

Oxygen therapy for rheumatology

Joint tissues (synovial membranes) swell up, there is disturbance in blood circulation and local tissues become anoxic (lacking in oxygen), thus slowing down cell metabolism. Hypoxia (oxygen deprival) is central to the effects of rheumatoid arthritis, as blood flow to the joint is decreased because of intra-articular pressure and the inflamed joints require increased levels of ...

ByOXYHELP INDUSTRY


Oxygen therapy for neurology

Oxygen therapy for neurology

Relief of Cerebral Hypoxia Oxygen deficiency is the cause of a pathological array of aggravating circumstances starting from the primary brain damage to hypoxia, aggravation of hypoxia, reaching to secondary brain damage. ...

ByOXYHELP INDUSTRY


HBOT for Complementary Therapy

HBOT for Complementary Therapy

It can be used in conjunction with other auxiliary therapies to treats medical conditions that include: Skin and soft tissues diseases: Thermal burns, chemical burns, radiation burns Frostbite Scalds Skin infections (erysipelas, pyoderma, actinomycosis, aspergillosis, Gram negative bacteria infections, nosocomial infections) Dry skin Cutaneous ulceration (caused by vein insufficiency , ...

ByOXYHELP INDUSTRY

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