Icp Ms Articles & Analysis
2 articles found
Elemental composition The presence of impurities in aluminum adjuvants can be determined using inductively coupled plasma mass spectrometry (ICP-MS). Differences in the type and amount of metal ions have been reported between AH adjuvants obtained from different manufacturers and from different batches, possibly due to differences in the sources of aluminum ...
These criteria, detailed in USP/, recommend analysis of drug products for element impurities by either ICP-AES or ICP-MS. Laboratories must measure impurities based on a J value for each drug product; drug products may be oral, parenteral (ex. intravenous, injection), or inhalation types. ...