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Immune Effector Articles & Analysis: Older

4 articles found

Differentiation and Functions of Th17/Treg Cytokines

Differentiation and Functions of Th17/Treg Cytokines

T cells are the most numerous and functionally complex type of lymphocytes, mainly including CD4+ T cells and CD8+ T2 cells, which play an important role in cellular immunity and assist in humoral immune response. According to their functions in the immune response, T lymphocytes mainly include helper T cells (Th cells), regulatory T cells (Treg ...

ByCreative Proteomics


Glycosylation of Fc Fusion Proteins: Insights into its Biological Significance

Glycosylation of Fc Fusion Proteins: Insights into its Biological Significance

Biological Significance of Glycosylation Changes in the glycan composition and structure of Fc-Fusion can cause conformational changes in the structural domain of Fc, which can alter its binding affinity to the Fcγ receptor and consequently lead to functional changes in immune effectors. Fc-mediated antibody effector functions include ...

ByCreative Proteomics


Immune Strategies for Cancer Treatment

Immune Strategies for Cancer Treatment

So which cells are best used for immunotherapies? Immune Checkpoint Inhibitors Controlling the strength and amplitude of an immune response is a critical feature of a healthy immune system. Dysregulation of this can cause a myriad of problems such as autoimmune diseases; there are therefore several mechanisms by which immune ...

Bylino Biotech AG


FluGen Announces Publication of Positive Results from Phase 2 Human Challenge Study of Its M2SR Vaccine Candidate Against Highly Drifted Strain of H3N2 Influenza Virus

FluGen Announces Publication of Positive Results from Phase 2 Human Challenge Study of Its M2SR Vaccine Candidate Against Highly Drifted Strain of H3N2 Influenza Virus

“The M2SR vaccine candidate is designed to induce a broad, multi-effector immune response, and this study demonstrated that subjects with vaccine-induced neutralizing antibodies were protected against infection and illness following challenge with an antigenically drifted virus. ...

ByFluGen, Inc.

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