Immune Efficacy Articles & Analysis: Older
4 articles found
In BALB/c mice, the transfection efficacy of frozen LUS-LNPs stored at −20°C for 12 months did not decrease and produced strong luciferase expression when compared with the fresh LNPs. ...
Peptide vaccines are increasingly seen as an economically efficient and safe approach to circumvent this issue.Peptide Vaccine DevelopmentThe vaccine development process is a challenging multi-step process: Antigen selection→Epitope selection→Adjuvant selection→Peptide vaccine synthesis→Immunization study→In vitro evaluation→Clinical trial.The development of peptide vaccines ...
About FluGen: FluGen, Inc. is a clinical-stage vaccine company transforming vaccine efficacy in respiratory diseases. The company’s lead candidate is M2SR, a supra-seasonal, live, single-replication, intranasal flu vaccine. Unlike standard of care flu vaccines, M2SR stimulates mucosal, humoral, and cellular immunity. In an unprecedented challenge trial, ...
Attenuated vaccines have become one of the important development directions due to their potential advantages in terms of immune effects, for example, attenuated influenza vaccines can be inoculated by intranasal spray that is simpler, economical, painless, and consistent with the natural route of infection; they can retain the natural structure of all or most antigens of the ...