immune functional Articles
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Copper in human health
Copper is an essential mineral for human health and at the same time can be toxic, depending upon the amounts ingested. Copper is associated with bone health, immune function and increased frequency of infections, cardiovascular risk and alterations in cholesterol metabolism. Its metabolism is tightly intertwined with other microminerals and its deficiency is known to impair iron mobilisation, ...
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Immune cells in Chernobyl radiation workers exposed to low dose irradiation
Immune response parameters were studied in Chernobyl radiation emergency workers exposed to low-dose irradiation during 1986–1989 and nuclear industry workers exposed under professional limits. Analysis was performed in irradiation dose limits of 250 and 100 mSv. The comparison group included participants of the clinical–epidemiological registry (n – 42,000) studied in the same time periods. The ...
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Infant malnutrition and chronic aflatoxicosis in Southern Africa: is there a link?
Malnutrition accounts for more than 5 million deaths of under-5s in the developing world annually. There is mounting evidence implicating aflatoxin contamination as an important factor in infant under-nutrition. Aflatoxins have in the past been associated with the development of primary liver cancer. More recent studies link chronic aflatoxicosis to infant growth stunting and increased morbidity ...
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Dietary fibre and human health
Food habits of new lifestyle have contributed to the appearance of chronic diseases such as obesity or cardiovascular diseases, which are mainly due to bad eating habits. Solutions can be found in providing the consumers with functional foods and health capability. Such food is rich in dietary fibre, with specific physicochemical behaviour and healthy properties. Dietary fibre rich food products ...
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Luminex Multiplex Assay
Principle of Luminex Multiplex Assay Luminex xMAP technology uses polystyrene microspheres of 5.6 microns in diameter dyed with different ratios of two red-sorting fluorescent dyes to obtain up to 100 fluorescent coded microspheres. Antibody molecules or gene probes for different test items are covalently cross-linked to specific coded microspheres, each of which corresponds to a specific test ...
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Food Sources and Effects of Carotenoids
Carotenoid structure and category The major carotenoids contain α-carotene, β-carotene, γ-carotene, lutein, zeaxanthin, β-cryptoxanthin, lycopene, etc. Among the three isomers of carotenoids, β-carotene has the highest content and γ-carotene the least. α, β, γ-carotene and β-cryptoxanthin can be decomposed to form vitamin A, while lutein, ...
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Understanding the Benefits of Probiotic Formula for Gut Health
The gut microbiota, a diverse community of microorganisms residing in our gastrointestinal tract, plays a crucial role in maintaining our overall health. Probiotics, live microorganisms with potential health benefits, have garnered significant attention for their ability to promote gut health. In this article, we will delve into the science behind probiotic formulas, exploring their mechanisms of ...
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Compound Active Probiotics Are Widely Used in the Field of Health
Probiotics are a class of active microorganisms that are beneficial to the host. They are the general term for active beneficial microorganisms that colonize the human intestine and reproductive system and can produce definite health effects to improve the host's micro-ecological balance and play a beneficial role. The beneficial bacteria or fungi in humans and animals mainly include: Clostridium ...
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Akkermansia muciniphila secretes a glucagon-like peptide-1-inducing protein that improves glucose homeostasis and ameliorates metabolic disease in mice
The gut microbiota, which includes Akkermansia muciniphila, is known to modulate energy metabolism, glucose tolerance, immune system maturation and function in humans1,2,3,4. Although A. muciniphila is correlated with metabolic diseases and its beneficial causal effects were reported on host metabolism5,6,7,8, the molecular mechanisms involved have not been identified. Here, we report thatA. ...
By KoBioLabs
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What are Strongyloides?
Strongyloides is an opportunistic pathogenic parasitic nematode. Adults parasitize in the small intestine of cats, dogs and humans. The larvae can invade lung, brain, liver, kidney and other tissues and organs, causing strongyloidiasis. The disease is mainly prevalent in warm and humid tropical and subtropical regions. In recent years, due to the continuous increase of HIV/AIDS infection rate in ...
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The Science Behind Dietary Supplements: Exploring Efficacy and Safety of Popular Ingredients
Dietary supplements have become increasingly popular in recent years as individuals seek to optimize their health and well-being. When it comes to popular dietary supplement ingredients, several categories stand out, including vitamins, minerals, amino acids, enzymes, botanicals, and more. Each of these components plays a crucial role in supporting various physiological functions in the human ...
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Suppressive effect on activation of macrophages by lactobacillus casei strain shirota genes determining the synthesis of cell wall-associated polysaccharides
Although many Lactobacillus strains used as probiotics are believed to modulate host immune responses, the molecular natures of the components of such probiotic microorganisms directly involved in immune modulation process are largely unknown. We aimed to assess the function of polysaccharide moiety of the cell wall of Lactobacillus casei strain Shirota as a possible immune modulator which ...
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8 Health Benefits of Taking Probiotics
Probiotics refer to a certain number of live microorganisms that can have a beneficial effect on the health of the host. At present, there are more than 20 kinds of probiotics used in China, mainly including Bifidobacterium, Lactobacillus, Clostridium butyricum, Saccharomyces boulardii, Enterococcus, Bacillus licheniformis and Bacillus cereus. Probiotics have eight major functions. 1. Maintain ...
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Detailed Introduction to the Four Effects of Probiotics
Probiotics, in simple terms, are a group of microorganisms that can effectively promote human health. They can resist gastric acid and bile acid, and can attach and colonize in the intestinal tract. According to statistics, the human gastrointestinal tract contains a rich and diverse microbial community, gathering more than 100 trillion microorganisms. These microbiomes encode more than 3 million ...
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Cytokines in CAR-T Cell Therapy
What is CAR T-cell therapy? Car-t cell therapy involves genetically engineering T cells isolated from patients or allogeneic donors to express chimeric antigen receptors (CAR) that specifically recognize and kill tumor cells. As a "living" drug, CAR-T therapy is very different from traditional drugs. It is a new type of precision targeted therapy for the treatment of tumors. Compared with ...
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Electronic cigarettes disrupt lung lipid homeostasis and innate immunity independent of nicotine
Abstract Electronic nicotine delivery systems (ENDS) or e-cigarettes have emerged as a popular recreational tool among adolescents and adults. Although the use of ENDS is often promoted as a safer alternative to conventional cigarettes, few comprehensive studies have assessed the long-term effects of vaporized nicotine and its associated solvents, propylene glycol (PG) and vegetable glycerin ...
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The Hidden Dangers and Facts of Cryotherapy: How to Remain Safe and Get Health benefits too
While cryotherapy or frost therapy has been used for millennia, the new cryotherapy center fad that's become popular in salon culture has come under scrutiny when a 24-year-old woman who worked at a cryohealth center in Las Vegas was found dead after using a cryo chamber at work. Learn more about cryotherapy, what it claims to do for the body, and whether or not it can be safely used. The ...
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ELife: T Interferon Suppresses Inflammatory Diseases by Balancing the Microbiome
The maintenance of immune homeostasis involves a synergistic relationship between the host and the microbiome. Canonical interferon (IFN) signaling controls the response to acute microbial infection through the involvement of STAT1 transcription factors. However, the contribution of tonic levels of interferon to immune homeostasis in the absence of acute infection remains largely unexplored. The ...
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Immune Strategies for Cancer Treatment
In the search for innovative and effective ways to target cancer, we are faced with more than just a challenging problem; we are faced with our own cells as opponents. Cancer cells evolve to achieve an optimum of physical fitness, giving them an array of abilities that no cell should possess in a healthy organism. One way to find novel therapies against cancer therefore could imply finding a ...
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Mechanism of Action of Paclitaxel
Paclitaxel is a natural anticancer drug with the molecular formula C47H51NO14. It has been widely used in the clinical treatment of breast cancer, ovarian cancer, and certain head and neck cancers, as well as lung cancer. Its novel and complex chemical structure, extensive and significant biological activity, unique mechanism of action, and scarce natural resources have gained immense favor among ...
By BOC Sciences
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