Immune Stimulating Articles & Analysis
13 articles found
When administered, these antigens stimulate the immune system to recognize and combat the actual pathogen without causing disease. ...
Adjuvants work by stimulating the innate immune system, which can lead to a stronger and longer-lasting immune response. ...
CpG is a type of oligodeoxynucleotide that can be used as an immune adjuvant to stimulate the maturation and development of antigen-presenting cells. ...
Chemokines: Chemokines are specialized cytokines that direct the migration of immune cells towards sites of infection or inflammation. They act as chemoattractants, guiding immune cells to the areas where they are needed most. ...
Among them, adjuvants play a crucial role in enhancing the immune response to vaccines, thereby increasing their effectiveness, notably as carriers, depots and stimulators of the immune response. Mechanism of Vaccine Adjuvants Vaccine excipients, including adjuvants, are added to vaccine formulations to enhance the immune ...
A new study by scientists at Scripps Research shows that the anxiety that develops during abstinence from excessive drinking can lead to relapse, and that anxiety may be caused in part by the release of immune proteins in the brain. The findings, published online recently in Molecular Psychiatry, shed light on the molecular details of the brain's response to alcohol addicts and ...
Cytokines are a class of small molecule proteins secreted by cells that mediate and regulate immune processes, and they act in an autocrine, paracrine and endocrine manner. ...
Using the power of large data and advanced computational methods, researchers can identify peptides on the surface of tumor cells and can target "peptide-centric" chimeric antigen receptors (PC-CARs): a new design of T cells that stimulates the immune response to eliminate tumors. The findings, published in Nature, open the door to the treatment of a wider ...
Natural killer (NK) cells are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. CD94 (Group of Differentiation 94), also known as Killer cell lectin-like receptor subfamily D member 1 (KLRD1), is expressed on the surface of natural killer cells in the innate immune system. ...
There are three key points in the research and development of RNA drugs: First, the immunogenicity of RNA drugs: because exogenous RNA will be recognized by the immune system as the signal of virus interference, RNA drugs will more or less stimulate the immune system, and then cause a series of side effects. ...
Researchers at Oxford University (UK) are intending to start animal trials imminently, and human trials next month, of a harmless virus intended to ‘smuggle’ coronavirus DNA into human cells and thus stimulate immunity. The vaccine, ChAdOx1, demonstrated promise for MERS and joins other experimental frontrunners currently in development across the ...
What differentiates pathogenic from asymptomatic antibodies is not fully understood, with the exception that there is some relationship between antibody concentration and occurrence of HIT, and that antibodies with the highest affinity to HPF4 are those with the strongest capacity to activate platelets. Probably, the immune response is first targeted to HPF4 complexes, but in ...
Single and fractionated WBI with 0.1 or 0.2 Gy, as well as the fractionated exposure to 1.0 Gy X-rays, significantly stimulated: the cytotoxicity of macrophages (Mφ) and Natural Killer (NK) cells mediated mainly by nitric oxide (NO) (Mφ) and perforin and Fas ligand (FasL) (NK cells); and production of IL-1β, IL-12 and TNF-α by Mφ, as well as the synthesis of IFN-γ by NK cells and ...