In Vitro Drug Articles & Analysis
3 articles found
Since these cells mimic the properties of the liver, researchers can evaluate the metabolism, drug-drug interaction and toxicity of drug candidates in a cost-effective manner. Pooled Human Cryopreserved Hepatocytes In drug development, primary human hepatocytes are the most suitable system for uptake, metabolism, clearance, ...
Researchers at the University of Helsinki and the University of Eastern Finland first searched for appropriate drug targets and reusable drugs and finally discovered six candidates with antiviral effects against SARS-CoV-2. ...
If tissues are available from individuals with appropriate genetic diversity, the consequences of specific mutations superimposed onto different genetic backgrounds can be observed, providing a better understanding of how drugs will perform across a population with a certain disease. Gene-Editing Opportunities for RepliGut® Models Altis Biosystems has developed ...