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In Vivo Conditions Articles & Analysis: Older

4 articles found

3D Co-culture Models

3D Co-culture Models

Cell cultures have played a significant role in the academy and pharmaceutical industry, but conventional 2D cultures fail to provide physiological relevance and communication network as compared to in vivo conditions, since they are unable to mimic the complexity of cellular microenvironment, an essential part for the cell behavior and systematic investigation. ...

ByCreative Bioarray


POLY MVA – a dietary supplement containing α-lipoic acid palladium complex, enhances cellular DNA repair

POLY MVA – a dietary supplement containing α-lipoic acid palladium complex, enhances cellular DNA repair

Administration of POLY MVA under post-irradiation conditions showed a decrease in the number of micronucleated reticulocytes. Thus, the studies under ex vivo and in vivo conditions revealed that the enhancement of DNA repair could be one of the mechanisms underlying radioprotection by POLY ...

ByInderscience Publishers


POLY MVA – a dietary supplement containing α-lipoic acid palladium complex, enhances cellular DNA repair

POLY MVA – a dietary supplement containing α-lipoic acid palladium complex, enhances cellular DNA repair

Administration of POLY MVA under post-irradiation conditions showed a decrease in the number of micronucleated reticulocytes. Thus, the studies under ex vivo and in vivo conditions revealed that the enhancement of DNA repair could be one of the mechanisms underlying radioprotection by POLY MVA. ...

ByInderscience Publishers


The contribution of communication between irradiated cells and between bystander cells to clonogenic survival and genomic instability

The contribution of communication between irradiated cells and between bystander cells to clonogenic survival and genomic instability

Clonogenic survival was not affected whether cells were allowed intercellular communication (reflecting in vivo conditions) or not. Genomic instability was induced under conditions permitting intercellular communication, but not when intercellular communication was prevented. Our results imply that cell survival following irradiation or bystander ...

ByInderscience Publishers

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