In Vivo Performance Articles & Analysis: Older
2 articles found
In many cases, their relatively large molecular weight (usually > 1000 Da) may affect oral bioavailability, solubility, and/or in vivo pharmacokinetic properties (not conforming to the Lipinski's Rule of Five). ...
Nanoconjugates have matured from simple devices to multifunctional, biodegradable, non–toxic and non–immunogenic constructs, capable of delivering synergistically functioning drugs in vivo. The present study evaluates the efficacy of drug polymer self folding nano–conjugates of pectin–cisplatin to enhance blood circulating levels of cisplatin. ...