In Vivo Response Articles & Analysis
4 articles found
It focuses on the relationship between drug concentration at the site of action and the resulting therapeutic or toxic response. In vivo PD studies allow for the observation of how a drug modulates biological pathways, providing insight into its potency, efficacy, and potential side effects. ...
Posterolateral Rabbit Spinal Fusion Study I. Introduction Autologous bone has long been the gold standard for bone graft substitute in spinal fusion procedures. The limited supply and morbidity associated with using autologous graft material led to the development of alternative bone grafting materials. Bioactive glass has a long history of biomedical use and has been shown to facilitate mineral ...
IL-2 regulates innate immune cells In humans, monocytes express IL-2R under the stimulation of IFN-γ, but only activated monocytes can bind with IL-2. During the inflammatory response, the expression of IL-2R will affect macrophage differentiation, limiting T cell proliferation and function. ...
As a representative species of nematodes, Caenorhabditis elegans is an attractive animal model for evaluating ecotoxicological effects and intrinsic mechanisms of stress response in vivo. To acquire a better knowledge of environmental effects of bisphenol A (BPA), ecotoxicological evaluations were conducted using C. elegans upon the physiological (growth, ...