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Inflammatory Factor Articles & Analysis

5 articles found

Differentiation and Functions of Th17/Treg Cytokines

Differentiation and Functions of Th17/Treg Cytokines

Th17 and Treg cells, two novel subsets of CD4+ T cells, have become a hot topic of research in the regulation of inflammatory responses. It has been found that the development of myasthenia gravis (MG), multiple sclerosis (MS) and Guillain-Barré syndrome (GBS) is associated with abnormalities of Th17 and Treg cells and cytokines and transcription factors. ...

ByCreative Proteomics


Inflammation, Immunity and Cancer

Inflammation, Immunity and Cancer

However, an excessive immune response can be harmful to the organism itself. The inflammatory response is an important active defense mechanism of the body, but chronic inflammation is one of the predisposing factors for cancer development. ...

ByCreative Proteomics


Cytokine Involvement in Inflammatory Immune Disorders

Cytokine Involvement in Inflammatory Immune Disorders

Cytokines in Cytokine Release Syndrome (CRS) CRS, a systemic inflammatory reaction stemming from diverse triggers such as infections, autoimmune inflammation, and medical causes, involves various cytokine classes including inflammatory effectors, initiators, modulators, chemokines, and colony-stimulating factors. ...

ByCreative Proteomics


Saving Us from Ourselves: Harnessing the Power of CAR-T to Combat Autoimmunity

Saving Us from Ourselves: Harnessing the Power of CAR-T to Combat Autoimmunity

What is autoimmune disease? Autoimmune disease a condition in which the body’s immune system mistakenly attacks the body itself. Thus far, more than 80 different autoimmune diseases have been identified, with some of the most prevalent including rheumatoid arthritis, Crohn’s disease, type 1 diabetes, and multiple sclerosis [1]. Autoimmune disease is one of the top ten causes of ...

ByIndee Labs


Epidermal growth factor-like domain repeat of stabilin-2 recognizes phosphatidylserine during cell corpse clearance

Epidermal growth factor-like domain repeat of stabilin-2 recognizes phosphatidylserine during cell corpse clearance

Clearance of apoptotic cells by a membrane PS receptor is one of the critical anti-inflammatory functions of macrophages. However, the PS binding receptors and their recognition mechanisms have not been fully investigated. Recently, we reported that stabilin-2 is a PS receptor that mediates the clearance of apoptotic cells, thus releasing the anti-inflammatory ...

ByAmerican Society for Microbiology (ASM)

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