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Influenza B Virus Articles & Analysis: Older

20 articles found

Frontiers in Antiviral Research 2024

Frontiers in Antiviral Research 2024

As we step into 2024, the global health landscape is increasingly focused on combatting viral infections, which continue to pose significant threats to public health. The COVID-19 pandemic has illuminated the critical need for innovative strategies in antiviral research, and scientists worldwide are embarking on groundbreaking projects to develop more effective therapies, vaccines, and preventive ...

ByBOC Sciences


Flu, COVID-19, and RSV in the U.S.: Insights from the Latest Surveillance Season

Flu, COVID-19, and RSV in the U.S.: Insights from the Latest Surveillance Season

Welcome to 2023-2024 season’s respiratory surveillance recap, where we’ll share insights from the most recent respiratory surveillance season, covering three major respiratory viruses: COVID-19, influenza, and RSV. Tracking these illnesses is imperative for maintaining population health because these illnesses significantly impact individual wellbeing and healthcare costs, resource ...

ByBiobot Analytics, Inc.


Scireq Softrestraint for Exposure Studies

Scireq Softrestraint for Exposure Studies

Evaluating the stress related effects of various restraint methods in rodents Any restraining device used in an inhalation exposure set-up will be, by definition, restricting the subject’s ability to move. For nose-only inhalation set-ups, typical restraints are rigid, fully enclosed and include a metal or acrylic plunger forcing the subject forward and preventing the subject from ...

BySCIREQ - an emka TECHNOLOGIES Company


Influenza A virus replication has a stronger dependency on Raf/MEK/ERK signaling pathway activity than SARS-CoV-2

Influenza A virus replication has a stronger dependency on Raf/MEK/ERK signaling pathway activity than SARS-CoV-2

The antiviral activity of zapnometinib treatment has been demonstrated for influenza virus infection in vivo (Laure et al., 2020; Koch-Heier et al., 2022) and influenza virus and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in vitro (Laure et al., 2020; Schreiber et al., 2020; Schreiber et al., 2022). ...

ByAtriva Therapeutics GmbH


API - Oseltamivir Phosphate

API - Oseltamivir Phosphate

These symptoms usually begin from 1-4 days (most commonly 1-2 days) after exposure to the virus and last for about 2-8 days[1]. There are four types of influenza virus: A, B, C, and D. Of these, the influenza A virus is responsible for most cases of severe illness, seasonal epidemics and ...

ByAlfa Chemistry


Project - Sublingual Interferon-alfa (BL SLIT II)

Project - Sublingual Interferon-alfa (BL SLIT II)

Respiratory syncytial virus, influenza virus, parainfluenza virus, adenovirus, rhinovirus, and coronavirus belong to the respiratory virus infections group. ...

ByBioLingus AG


Ozette’s AI in the battle against Covid - Case study

Ozette’s AI in the battle against Covid - Case study

Summary The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic began in 2019 and rapidly scaled to a global presence of disease known as COVID-19. Despite the relatively fast implementation of testing and vaccination worldwide, the rise of emerging viral variants and breakthrough infections raises concerns that SARS-CoV-2 will continue to pose a global health threat. ...

ByOzette Technologies


Nature Biotechnology: Generation of a live attenuated influenza A vaccine by proteolysis targeting

Nature Biotechnology: Generation of a live attenuated influenza A vaccine by proteolysis targeting

Longlong Si's research group from the Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, published a research titled "Generation of a live attenuated influenza A vaccine by proteolysis targeting" in Nature Biotechnology. Using influenza virus as a model virus, the team established the technology of protein degradation targeting virus as an ...

ByProfacgen


Cytokine Storms and Viral Infections

Cytokine Storms and Viral Infections

Cytokines are small soluble proteins that are secreted by immune cells and tissue cells to play a regulatory role between cells, including interferon (IFN), interleukin (IL), chemokines, colony-stimulating factors (CSF), tumor necrosis factors (TNF) and so on. Cytokines function in autocrine, paracrine or endocrine forms, and can regulate cell growth and differentiation, modulate immune response ...

ByCreative Proteomics


The Network that Makes Seasonal Flu Vaccines Possible

The Network that Makes Seasonal Flu Vaccines Possible

Influenza is constantly mutating. 70 years ago, the World Health Organization set up a surveillance network to protect people from its threat. Making influenza vaccines that can help protect against viruses that threaten human health isn’t a simple process. It requires the cooperation between influenza vaccine manufacturers like Seqirus, and the World Health Organization’s ...

ByCSL Seqirus UK Limited


FluGen Announces First Subject Dosed in Phase 1b Clinical Trial of its Intranasal M2SR Flu Vaccine, Co-Administered with High Dose Vaccine, in Older Adults

FluGen Announces First Subject Dosed in Phase 1b Clinical Trial of its Intranasal M2SR Flu Vaccine, Co-Administered with High Dose Vaccine, in Older Adults

Study will measure immune responses generated by M2SR and high dose vaccine separately and in combination in the highly vulnerable 65-85 years old population – Funded by the US Department of Defense, this study is expected to yield topline data in 2H 2022 – MADISON, Wis., June 22, 2022 /PRNewswire/ — FluGen, Inc., a clinical-stage vaccine company transforming vaccine ...

ByFluGen, Inc.


Under Sewer-Veillance - Wastewater & COVID-19

Under Sewer-Veillance - Wastewater & COVID-19

Wastewater & COVID-19 Connections When the word wastewater crosses your mind, there is probably also a memory of your Mom’s voice telling you – wash your hands! When humans transitioned into community living, keeping your living space separate from your bathroom space was an important rule to learn. We can thank early scientists who were curious about how diseases spread and ...

ByFlottweg SE


FluGen Announces Publication of Positive Results from Phase 2 Human Challenge Study of Its M2SR Vaccine Candidate Against Highly Drifted Strain of H3N2 Influenza Virus

FluGen Announces Publication of Positive Results from Phase 2 Human Challenge Study of Its M2SR Vaccine Candidate Against Highly Drifted Strain of H3N2 Influenza Virus

Data published in the Journal of Infectious Diseases demonstrate that M2SR can protect against a multi-seasonal, seven-year drifted influenza strain – MADISON, Wis., Aug. 2, 2021 /PRNewswire/ — FluGen, Inc., a clinical-stage vaccine company transforming vaccine efficacy in infectious respiratory diseases, today announced the publication of results from its Phase 2 human challenge ...

ByFluGen, Inc.


FluGen Initiates NIH-Funded Trial of M2SR Flu Vaccine; First Study in Adults Up to Age 85

FluGen Initiates NIH-Funded Trial of M2SR Flu Vaccine; First Study in Adults Up to Age 85

Study will measure immune responses to matched and drifted virus strains in older adults, a population that is most vulnerable to mortality from flu – Topline data expected in 1H 2022 – MADISON, Wis., May 25, 2021 /PRNewswire/ — FluGen, Inc., a clinical-stage vaccine company transforming vaccine efficacy in infectious respiratory diseases, today announced the initiation of the ...

ByFluGen, Inc.


Creative Enzymes Launches Advanced Neuraminidase for Flu Vaccine Development

Creative Enzymes Launches Advanced Neuraminidase for Flu Vaccine Development

Creative Enzymes, a professional enzyme provider located in New York, always hammers at researches and trials in order to provide customers with various enzymes as many as possible. Last week, the product manager of Creative Enzymes announced the launch of neuraminidase, which is expected to further develop a new universal influenza vaccine. Neuraminidase is a drug target to prevent the spread ...

ByCreative Enzymes


UW–Madison, FluGen, Bharat Biotech to develop CoroFlu, a coronavirus vaccine

UW–Madison, FluGen, Bharat Biotech to develop CoroFlu, a coronavirus vaccine

MADISON, Wis.–(BUSINESS WIRE)–An international collaboration of virologists at the University of Wisconsin–Madison and the vaccine companies FluGen and Bharat Biotech has begun the development and testing of a unique vaccine against COVID-19 called CoroFlu. UW–Madison, FluGen, Bharat Biotech to develop CoroFlu, a coronavirus vaccineTweet this CoroFlu will build on the ...

ByFluGen, Inc.


Single-replication BM2SR vaccine provides sterilizing immunity and cross-lineage influenza B virus protection in mice

Single-replication BM2SR vaccine provides sterilizing immunity and cross-lineage influenza B virus protection in mice

There are two antigenically distinct lineages of influenza B virus, Yamagata lineage (YL) and Victoria lineage (VL). Since both B lineages have been co-circulating for years, more than 70% of influenza vaccines currently manufactured are quadrivalent consisting of influenza A (H1N1), ...

ByFluGen, Inc.


Surveillance of Influenza A and the pandemic influenza A (H1N1) 2009 in sewage and surface water in the Netherlands

Surveillance of Influenza A and the pandemic influenza A (H1N1) 2009 in sewage and surface water in the Netherlands

The role of the water cycle in spreading human pathogenic influenza viruses is poorly studied and is not considered to be significant. However, gastrointestinal symptoms developed in a large proportion of influenza A (H1N1) 2009 virus infected people during the pandemic in 2009 and fecal shedding was reported. This fecal route could potentially play a role in the entry of human pathogenic ...

ByIWA Publishing


Simulation to assess the efficacy of US airport entry screening of passengers for pandemic influenza

Simulation to assess the efficacy of US airport entry screening of passengers for pandemic influenza

We present our methodology and stochastic discrete-event simulation developed to model the screening of passengers for pandemic influenza at the US port-of-entry airports. Our model uniquely combines epidemiology modelling, evolving infected states and conditions of passengers over time, and operational considerations of screening in a single simulation. The simulation begins with international ...

ByInderscience Publishers


Significance of fomites in the spread of respiratory and enteric viral disease

Significance of fomites in the spread of respiratory and enteric viral disease

Worldwide annually there are 1.7 million deaths from diarrheal diseases and 1.5 million deaths from respiratory infections (56). Viruses cause an estimated 60% of human infections, and most common illnesses are produced by respiratory and enteric viruses (7, 49). Unlike bacterial disease, viral illness cannot be resolved with the use of antibiotics. Prevention and management of viral disease ...

ByAmerican Society for Microbiology (ASM)

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