intestinal mucosa Articles
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Applications of Diamine Oxidase
Diamine oxidase (DAO) is an intracellular enzyme that catalyzes diamine in mucosal or ciliated epithelial cells of the mammalian small intestine. It protects the intestinal mucosa by regulating intracellular ion homeostasis, influencing conduction pathways, and promoting cellular repair. Serum DAO is elevated in small intestinal mucosal barrier failure or in intestinal mucosal cell necrosis; ...
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The Importance of Moderate Supplementation of Intestinal Lactase
Lactase is a disaccharidase present on the surface of mammalian small intestinal mucosal microvilli, and many beneficial intestinal bacteria have the ability to produce lactase. Lactase deficiency is present in most of the world's population, affecting nearly 2/3 of the world's population. Polylactose is composed of glucose and galactose, these two monosaccharides are easily absorbed by the ...
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Function and Detection of Bile Acids
What is Bile Acid? Bile acids are the main components of bile and are synthesized in the liver from cholesterol through a series of enzymatic reactions. Bile acids can be divided into free bile acids and conjugated bile acids according to their structures. Free bile acids include bile acids, goose deoxycholic acid, deoxycholic acid and lithophanic acid. The above free bile acids are combined ...
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What are Strongyloides?
Strongyloides is an opportunistic pathogenic parasitic nematode. Adults parasitize in the small intestine of cats, dogs and humans. The larvae can invade lung, brain, liver, kidney and other tissues and organs, causing strongyloidiasis. The disease is mainly prevalent in warm and humid tropical and subtropical regions. In recent years, due to the continuous increase of HIV/AIDS infection rate in ...
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Exploring the Intricate Link Between Bile Acids and Disease
Bile acids are synthesized in the liver from cholesterol as a raw material. As a natural "emulsifier", they can promote the dissolution, digestion and absorption of fats, fat-soluble vitamins, etc. Meanwhile, as an important signaling molecule, bile acids can activate the relevant receptors to maintain the homeostasis of hepatic glucose and lipid metabolism, and interact with gut bacteria to ...
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Exploring the Role of Enzyme Technology in Advancing Dairy Research
With the rapid development of the dairy cattle breeding industry and the dairy industry, the output of raw milk and dairy products has increased significantly, the variety of dairy products has been greatly enriched, and the quality has also made a qualitative leap. High and new technologies such as gene technology, enzyme technology, microbial technology, high-pressure technology, and cold ...
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Bile Acid: A Comprehensive Exploration of Function and Metabolism
In the realm of biological sciences, bile acids stand as pivotal molecules, playing a multifaceted role in various physiological processes within organisms. Bile acids are specialized molecules synthesized from cholesterol within the liver. These amphipathic compounds possess a hydrophilic region (carboxylic acid moiety) and a hydrophobic region (steroid backbone). Their distinctive structure ...
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The Power Of RepliGut in Vitro Intestinal Stem Cell Models
Both current in vitro and in vivo models used in the development of candidate therapies for the treatment of intestinal diseases have severe limitations. RepliGut®, an in vitro human intestinal epithelial stem cell model, addresses many of these issues and has significant potential to reduce the time and cost of drug development. This model may even help to identify optimal therapies for ...
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Recapitulating the Multifaceted Inflammatory Environment of the Intestine In Vitro
Intestinal inflammatory diseases are highly complex, which has thus far prevented development of an effective in vitro disease model. With access to a donor-derived cell biobank and the ability to recapitulate region-specific environments of the intestine, Altis Biosystems is working toward the development of an in vitro RepliGut® model to accurately recapitulate the complex intestinal ...
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