intravenous injection Articles
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Everything You Want to Know About Lipoprotein Lipase
Lipoprotein lipase (LPL) is a glycoprotein synthesized and secreted by parenchymal cells such as adipocytes, cardiomyocytes, skeletal muscle cells, mammary cells, and macrophages, with a molecular weight of 60ku and containing 3-8% carbohydrates. The physiological function of LPL is to catalyze the breakdown of TG in the core of CM and VLDL into fatty acids and monoglycerides for tissue oxidative ...
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Measurement of Elemental Impurities in a Higher Daily Dose Drug Product by USP <232>/<233> Using Ultrasonic Nebulization with ICP-AES Detection
Abstract: On January 1, 2018 the U.S. Pharmacopeia (USP) enacted new criteria for element impurities in finished drug products. These criteria, detailed in USP/, recommend analysis of drug products for element impurities by either ICP-AES or ICP-MS. Laboratories must measure impurities based on a J value for each drug product; drug products may be oral, parenteral (ex. intravenous, injection), or ...
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Project - Sublingual Interferon-alfa (BL SLIT II)
We plan to develop sublingual interferon-alfa for the prevention of viral infections, such as influenza and coronaviruses (such as COVID-19). The rise in prevalence of viral respiratory infections in humans and increase in health care expenditure are projected to boost the growth of the global respiratory antiviral treatment market. Respiratory syncytial virus, influenza virus, parainfluenza ...
By BioLingus AG
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Development of mRNA-Directed Delivery - LNP Delivery System
During the COVID-19 pandemic, the success of mRNA vaccines has greatly propelled the development of mRNA therapeutics. mRNA is a negatively charged nucleic acid that serves as a template for protein synthesis in ribosomes. Despite its utility, the instability of mRNA necessitates appropriate carriers for in vivo delivery. Currently, lipid nanoparticles (LNPs) are the most mature approach for ...
By BOC Sciences
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The first CRISPR gene editing of vascular endothelium was made possible thanks to nanoparticles
The vascular endothelium is a single layer of endothelial cells that lines the surface of the vascular lumen, and it plays an important role in maintaining vascular homeostasis and tissue fluid balance. Many disorders, such as coronary artery disease, stroke, bronchopulmonary dysplasia, and pulmonary hypertension, are caused by endothelial dysfunction. Genome editing in endothelial cells can also ...
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Rani Therapeutics Debuts on the Nasdaq: What uou should know About the Biopharma
IMPORTANT MESSAGE: Benzinga prides itself as a media platform that is "For the People, By the People." We understand the markets are scary right now. For that reason, we are here to help. For today only get access to our #1 Options Newsletter for only $1. Rani Therapeutics Holdings, Inc. RANI+ Free Alerts, a San Jose, California-based early stage biopharma, debuted Friday on the Nasdaq ...
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The Reality and Future of Peptide Drugs
It has been said that the 21st century is the century of peptide drugs, and the fate of this substance, which lies between a large protein and a small molecule compound, is bound to be extraordinary. What are peptide drugs? Peptides are a class of compounds made up of amino acids linked by peptide bonds and are chemically active substances commonly found in living organisms. According to the ...
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What are the ADC drugs?
Antibody-drug conjugates (ADCs) continue to rise at home and abroad, but ADCs are not a new thing. Why has ADC been surging for so many years? What kind of magic power it contains, and what makes its growth path so tortuous? Let's take a brief look at the magical "magic bullet"-ADC. ADC (antibody-conjugated drug) is not a new concept. As early as the early 20th century, the Nobel Prize winner ...
By BOC Sciences
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Surgery for Carpal Tunnel
Considering Surgery for Carpal Tunnel Syndrome? Carpal tunnel syndrome (CTS) is a painful or numbing condition that affects the hands and fingers. It’s caused by pressure on one main nerves of the hand, the median nerve. The nerve passes through a narrow passageway in the wrist called the “carpal tunnel” (hence the name of the disorder). The pressure causes the nerve to ...
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The Limitations and Challenges of Cancer Therapies
Considerable investment into cancer research has led to the development of remarkable new therapies, which have greatly improved therapeutic outcome for the countless individuals diagnosed with cancer. Until recently, almost all therapies that were granted clinical approval were small molecules. However, biotechnological advances in the last several decades have made it possible to develop ...
By Indee Labs
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California Prop65 list
1. Tetrahydrocannabinol (THC) Tetrahydrocannabinol (THC) is an active ingredient in Nabiximols, a specific extract of Cannabis that was approved as a botanical drug in the United Kingdom since 2010 as a mouth spray for people with multiple sclerosis to reduce neuropathic pain, spasticity, overactive bladder, and other symptoms. Nabiximols (as Sativex) is available as a prescription drug in ...
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