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Kinase Assay Articles & Analysis

1 articles found

Assessing the mutagenic effect potential of pharmaceuticals and of their transformation products. Implications in the gene expression profiling

Assessing the mutagenic effect potential of pharmaceuticals and of their transformation products. Implications in the gene expression profiling

The present study embraces this complexity, providing an integrated approach to assess the potential effects of transformation products of pharmaceuticals by means of mutagenicity, estrogenicity and differences in the gene expression profiles. Mutagenicity using the tk kinase assay was applied to assess a list of eleven priority pharmaceuticals namely atenolol, ...

ByJohn Wiley & Sons, Ltd.

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