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Lc Ms Articles & Analysis: This-Year
7 articles found
The workflow typically involves high-resolution mass spectrometry (LC-MS/MS) coupled with sophisticated enrichment strategies. First, proteins are extracted from cells or tissues and digested into smaller peptides. ...
Using specialized tools like antibodies that recognize the unique signature left after ubiquitin digestion (the "di-glycine remnant" or K-GG motif), scientists can selectively isolate ubiquitinated peptides from a cell lysate. Mass Spectrometry (LC-MS/MS): This enriched sample is then analyzed by liquid chromatography-tandem mass spectrometry ...
The gold standard for Sterol Lipids Analysis is a combination of chromatography and mass spectrometry (LC-MS/MS or GC-MS/MS). Chromatography (LC or GC): This first step acts like a molecular sorting system, separating the different sterol lipids from each other and from other molecules in the ...
The Technical Revolution in Glycan Analysis Modern glycomics leverages breakthrough technologies that have transformed the field: Nano-LC-MS/MS with electron-transfer dissociation capturing fragmentation patterns impossible with earlier techniques Isotope-coded glycan tagging enabling precise quantitative comparisons across disease states ...
Advanced methods, such as liquid chromatography-tandem mass spectrometry (LC-MS/MS), are indispensable tools. They allow researchers to: (1) Investigate Endocrine Mechanisms: Advanced analysis techniques help researchers study steroid hormone imbalances associated with various conditions, including cortisol dysregulation, reproductive ...
Creative Proteomics offers specialized glucosinolates analysis services using advanced technologies like LC-MS and GC-MS, enabling researchers to identify, quantify, and profile glucosinolates in various sample types. Key Analytical Techniques Liquid Chromatography-Mass Spectrometry (LC-MS): ...
One of the most effective methods is mass spectrometry (MS), often combined with liquid chromatography (LC-MS). This technology enables the detailed identification and quantification of lipids and metabolites from small samples like exosomes, which are typically limited in number. ...